Prospidium chloride

Prospidium chloride

Names
IUPAC name 1-chloro-3-[12-(3-chloro-2-hydroxypropyl)-3,12-diaza-6,9-diazoniadispiro[5.2.59.26]hexadecan-3-yl]propan-2-ol dichloride
Other names Prospidine
Identifiers
CAS Number	23476-83-7 Y
ChEMBL	ChEMBL509176 N
Jmol interactive 3D	Image
PubChem	78921313
UNII	7G733H6RES N
SMILES C1C[N+]2(CCN1CC(CCl)O)CC[N+]3(CCN(CC3)CC(CCl)O)CC2.[Cl-].[Cl-]
Properties
Chemical formula	C18H36Cl4N4O2
Molar mass	482.31 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Prospidium chloride is a spiro compound.

Definition of Prospidin: A Russian Drug, a dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophages. This compound had a registration for Squamous Cell Carcinoma of the Head&Neck, reports exist about its activity in HIV-Related Kaposi Sarcoma. Prospidin has good anti-lupus activity due to its immunosuppressant effects and was also used in refractory Rheumatoid Arthritis as an anti-rheumatic drug. Usually, it has no Hematologic Toxicity. (NCI04) Prospidin is from the group

DNA Adduct Forming Agent Immunosuppressant

Other Names for Prospidin

Prospidin

3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, dichloride

Prospidine

Prospidium

Prospidium Chloride