Prosolanapyrone-III cycloisomerase

Prosolanapyrone-III cycloisomerase
Identifiers
EC number 5.5.1.20
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Prosolanapyrone-III cycloisomerase (EC 5.5.1.20, Sol5, SPS, solanapyrone synthase (bifunctional enzyme: prosolanapyrone II oxidase/prosolanapyrone III cyclosiomerase)) is an enzyme with system name prosolanapyrone-III:(-)-solanapyrone A isomerase.[1][2][3] This enzyme catalyses the following chemical reaction

prosolanapyrone III \rightleftharpoons (-)-solanapyrone A

The enzyme is involved in the biosynthesis of the phytotoxin solanapyrone in some fungi.

References

  1. Kasahara, K., Miyamoto, T., Fujimoto, T., Oguri, H., Tokiwano, T., Oikawa, H., Ebizuka, Y. and Fujii, I. (2010). "Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani". Chembiochem. 11: 1245–1252. doi:10.1002/cbic.201000173. PMID 20486243.
  2. Katayama, K., Kobayashi, T., Oikawa, H., Honma, M. and Ichihara, A. (1998). "Enzymatic activity and partial purification of solanapyrone synthase: first enzyme catalyzing Diels-Alder reaction". Biochim. Biophys. Acta 1384 (2): 387–395. doi:10.1016/s0167-4838(98)00040-5. PMID 9659400.
  3. Katayama, K., Kobayashi, T., Chijimatsu, M., Ichihara, A. and Oikawa, H. (2008). "Purification and N-terminal amino acid sequence of solanapyrone synthase, a natural Diels-Alderase from Alternaria solani". Biosci. Biotechnol. Biochem. 72 (2): 604–607. doi:10.1271/bbb.70600. PMID 18256508.

External links

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