Prolycopene isomerase

Prolycopene isomerase (EC 5.2.1.13, CRTISO, carotene cis-trans isomerase, ZEBRA2 (gene), carotene isomerase, carotenoid isomerase) is an enzyme with system name 7,9,7',9'-tetracis-lycopene cis-trans-isomerase.^[1]^[2]^[3]^[4] This enzyme catalyses the following chemical reaction

7,9,7',9'-tetracis-lycopene

\rightleftharpoons

all-trans-lycopene

This enzyme is involved in carotenoid biosynthesis.

References

↑ Yu, Q., Ghisla, S., Hirschberg, J., Mann, V. and Beyer, P. (2011). "Plant carotene cis-trans isomerase CRTISO: a new member of the FADred-dependent flavoproteins catalyzing non-redox reactions". J. Biol. Chem. 286: 8666–8676. doi:10.1074/jbc.m110.208017. PMID 21209101.
↑ Li, Q., Farre, G., Naqvi, S., Breitenbach, J., Sanahuja, G., Bai, C., Sandmann, G., Capell, T., Christou, P. and Zhu, C. (2010). "Cloning and functional characterization of the maize carotenoid isomerase and β-carotene hydroxylase genes and their regulation during endosperm maturation". Transgenic Res. 19: 1053–1068. doi:10.1007/s11248-010-9381-x. PMID 20221689.
↑ Isaacson, T., Ronen, G., Zamir, D. and Hirschberg, J. (2002). "Cloning of tangerine from tomato reveals a carotenoid isomerase essential for the production of β-carotene and xanthophylls in plants". Plant Cell 14: 333–342. doi:10.1105/tpc.010303. PMID 11884678.
↑ Chai, C., Fang, J., Liu, Y., Tong, H., Gong, Y., Wang, Y., Liu, M., Wang, Y., Qian, Q., Cheng, Z. and Chu, C. (2011). "ZEBRA2, encoding a carotenoid isomerase, is involved in photoprotection in rice". Plant Mol. Biol. 75: 211–221. doi:10.1007/s11103-010-9719-z. PMID 21161331.

External links

Prolycopene isomerase at the US National Library of Medicine Medical Subject Headings (MeSH)

Isomerases: geometric (EC 5.2)

5.2.1	FKBP: FKBP1A FKBP1B FKBP2 FKBP3 FKBP5 FKBP6 FKBP8 FKBP9 FKBP10 FKBP52 FKBPL other: Cyclophilin Parvulin Prolyl isomerase

Proteins: enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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