Persephin

persephin
Identifiers
Symbol	PSPN
Entrez	5623
HUGO	9579
OMIM	602921
RefSeq	NM_004158
UniProt	O60542
Other data
Locus	Chr. 19 p13.3

Persephin is a neurotrophic factor in the glial cell line-derived neurotrophic factor (GDNF) family.

External links

persephin at the US National Library of Medicine Medical Subject Headings (MeSH)

Cell signaling: nervous tissue: neurotrophin

Trk binding	NGF BDNF NT-3 NT-4

GFL	GDNF Neurturin Artemin Persephin

Other	CNTF GMF IGF-1 Neuregulin (1, 2, 3, 4) PACAP VEGF

Neurotrophinergics

Agonists: Axokine
CNTF

Agonists: BDNF
NGF
NT-3
NT-4

Antagonists: SAR127963

GFRα1	Agonists: GDNF

GFRα2	Agonists: Neurturin (NRTN)

GFRα3	Agonists: Artemin (ARTN)

GFRα4	Agonists: Persephin (PSPN)

TrkA	Agonists: Amitriptyline Gambogic amide NGF Tavilermide Antagonists: FX007

TrkB	Agonists: 3,7-DHF 3,7,8,2'-THF 4'-DMA-7,8-DHF 7,3'-DHF 7,8-DHF 7,8,2'-THF 7,8,3'-THF Amitriptyline BDNF Deoxygedunin Diosmetin HIOC LM22A-4 N-Acetylserotonin NT-3 NT-4 Norwogonin (5,7,8-THF) R7 TDP6 Antagonists: ANA-12 Cyclotraxin B Gossypetin (3,5,7,8,3',4'-HHF) Inhibitors: K252a

TrkC	Agonists: NT-3

Others

Antibodies: Tanezumab (against NGF)

Others: Cerebrolysin (neurotrophin mixture)

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