DBP (gene)

D site of albumin promoter (albumin D-box) binding protein
Identifiers
Symbols DBP ; DABP
External IDs OMIM: 124097 MGI: 94866 HomoloGene: 1035 GeneCards: DBP Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 1628 13170
Ensembl ENSG00000105516 ENSMUSG00000059824
UniProt Q10586 Q60925
RefSeq (mRNA) NM_001352 NM_016974
RefSeq (protein) NP_001343 NP_058670
Location (UCSC) Chr 19:
48.63 – 48.64 Mb		 Chr 7:
45.71 – 45.71 Mb
PubMed search

D site of albumin promoter (albumin D-box) binding protein, also known as DBP, is a protein which in humans is encoded by the DBP gene.[1][2]

DBP is a member of the PAR bZIP (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family.[1][3] DBP binds to an upstream promoter in the insulin gene.[4]

References

  1. 1 2 "Entrez Gene: DBP D site of albumin promoter (albumin D-box) binding protein".
  2. ↑ Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (Jun 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics 13 (2): 293–300. doi:10.1016/0888-7543(92)90245-N. PMID 1535333.
  3. ↑ Khatib ZA, Inaba T, Valentine M, Look AT (Sep 1994). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes". Genomics 23 (2): 344–51. doi:10.1006/geno.1994.1510. PMID 7835883.
  4. ↑ Melloul D, Marshak S, Cerasi E (Mar 2002). "Regulation of insulin gene transcription". Diabetologia 45 (3): 309–26. doi:10.1007/s00125-001-0728-y. PMID 11914736.

Further reading

  • Brown SA, Schibler U (Oct 1999). "The ins and outs of circadian timekeeping". Current Opinion in Genetics & Development 9 (5): 588–94. doi:10.1016/S0959-437X(99)00009-X. PMID 10508692. 
  • Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (Jun 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics 13 (2): 293–300. doi:10.1016/0888-7543(92)90245-N. PMID 1535333. 
  • Khatib ZA, Inaba T, Valentine M, Look AT (Sep 1994). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes". Genomics 23 (2): 344–51. doi:10.1006/geno.1994.1510. PMID 7835883. 
  • Nyunoya H, Morita T, Sato T, Honma S, Tsujimoto A, Shimotohno K (Oct 1994). "Cloning of a cDNA encoding a DNA-binding protein TAXREB302 that is specific for the tax-responsive enhancer of HTLV-I". Gene 148 (2): 371–3. doi:10.1016/0378-1119(94)90716-1. PMID 7958972. 
  • Nyunoya H, Morita T, Sato T, Honma S, Tsujimoto A, Shimotohno K (Apr 1993). "Cloning of a cDNA encoding a DNA-binding protein TAXREB302 that is specific for the tax-responsive enhancer of HTLV-I". Gene 126 (2): 251–5. doi:10.1016/0378-1119(93)90375-D. PMID 8482542. 
  • Picketts DJ, Lillicrap DP, Mueller CR (Feb 1993). "Synergy between transcription factors DBP and C/EBP compensates for a haemophilia B Leyden factor IX mutation". Nature Genetics 3 (2): 175–9. doi:10.1038/ng0293-175. PMID 8499951. 
  • Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474. 
  • Shutler G, Glassco T, Kang X, Korneluk R, Mueller CR (Jun 1996). "Genomic structure of the human D-site binding protein (DBP) gene". Genomics 34 (3): 334–9. doi:10.1006/geno.1996.0295. PMID 8786133. 
  • Stubbs L, Carver E, Ashworth L, Lopez-Molina L (Jan 1996). "Location of the DBP transcription factor gene in human and mouse". Mammalian Genome 7 (1): 65–7. doi:10.1007/s003359900016. PMID 8903733. 
  • Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174. 
  • Begbie M, Mueller C, Lillicrap D (Feb 1999). "Enhanced binding of HLF/DBP heterodimers represents one mechanism of PAR protein transactivation of the factor VIII and factor IX genes". DNA and Cell Biology 18 (2): 165–73. doi:10.1089/104454999315556. PMID 10073576. 
  • Lamprecht C, Mueller CR (Jun 1999). "D-site binding protein transactivation requires the proline- and acid-rich domain and involves the coactivator p300". The Journal of Biological Chemistry 274 (25): 17643–8. doi:10.1074/jbc.274.25.17643. PMID 10364202. 
  • Yan L, Miyake S, Okamura H (Jan 2000). "Distribution and circadian expression of dbp in SCN and extra-SCN areas in the mouse brain". Journal of Neuroscience Research 59 (2): 291–5. doi:10.1002/(SICI)1097-4547(20000115)59:2<291::AID-JNR16>3.0.CO;2-O. PMID 10650888. 
  • Smith JS, Tachibana I, Pohl U, Lee HK, Thanarajasingam U, Portier BP, Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN, Jenkins RB (Feb 2000). "A transcript map of the chromosome 19q-arm glioma tumor suppressor region". Genomics 64 (1): 44–50. doi:10.1006/geno.1999.6101. PMID 10708517. 
  • Newman JR, Keating AE (Jun 2003). "Comprehensive identification of human bZIP interactions with coiled-coil arrays". Science 300 (5628): 2097–101. doi:10.1126/science.1084648. PMID 12805554. 
  • Sethunarayanan SR (2011). "D-site of albumin promoter binding protein may regulate hematopoiesis" (PDF). Biol. Med. 3 (3): 32–69. 

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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