OR6B1
Olfactory receptor, family 6, subfamily B, member 1 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | OR6B1 ; OR7-3; OR7-9 | ||||||||||||
External IDs | MGI: 3030283 HomoloGene: 17485 GeneCards: OR6B1 Gene | ||||||||||||
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Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 135946 | 259067 | |||||||||||
Ensembl | ENSG00000221813 | ENSMUSG00000049168 | |||||||||||
UniProt | O95007 | Q8VGW8 | |||||||||||
RefSeq (mRNA) | NM_001005281 | NM_147064 | |||||||||||
RefSeq (protein) | NP_001005281 | NP_667275 | |||||||||||
Location (UCSC) |
Chr 7: 144 – 144 Mb |
Chr 6: 42.84 – 42.84 Mb | |||||||||||
PubMed search | |||||||||||||
Olfactory receptor 6B1 is a protein that in humans is encoded by the OR6B1 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
Further reading
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
External links
- OR6B1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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