OR5B12
Olfactory receptor, family 5, subfamily B, member 12 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | OR5B12 ; OR11-241; OR5B12P; OR5B16; OST743 | ||||||||||||
External IDs | MGI: 3031282 HomoloGene: 133606 GeneCards: OR5B12 Gene | ||||||||||||
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RNA expression pattern | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 390191 | 258694 | |||||||||||
Ensembl | ENSG00000172362 | ENSMUSG00000045126 | |||||||||||
UniProt | Q96R08 | Q8VFX1 | |||||||||||
RefSeq (mRNA) | NM_001004733 | NM_146699 | |||||||||||
RefSeq (protein) | NP_001004733 | NP_666910 | |||||||||||
Location (UCSC) |
Chr 11: 58.44 – 58.44 Mb |
Chr 19: 12.88 – 12.88 Mb | |||||||||||
PubMed search | |||||||||||||
Olfactory receptor 5B12 is a protein that in humans is encoded by the OR5B12 gene.[1][2]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]
See also
References
- ↑ Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (Sep 2002). "DEFOG: a practical scheme for deciphering families of genes". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- 1 2 "Entrez Gene: OR5B12 olfactory receptor, family 5, subfamily B, member 12".
Further reading
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
External links
- OR5B12 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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