Nogalamycin

Nogalamycin
Identifiers

CAS Number	1404-15-5^Y
ChemSpider	4451071^N
Jmol interactive 3D	Image
PubChem	5289019
UNII	L059DCD6IP^Y
InChI InChI=1S/C39H49NO16/c1-14-32(49-7)39(4,52-10)33(50-8)36(53-14)54-19-13-37(2,48)24(34(47)51-9)15-11-16-21(27(43)20(15)19)28(44)22-18(41)12-17-30(23(22)26(16)42)55-35-29(45)25(40(5)6)31(46)38(17,3)56-35/h11-12,14,19,24-25,29,31-33,35-36,41,43,45-46,48H,13H2,1-10H3/t14-,19-,24-,25-,29-,31+,32-,33-,35+,36-,37-,38+,39+/m0/s1^N Key: KGTDRFCXGRULNK-JYOBTZKQSA-N^N InChI=1/C39H49NO16/c1-14-32(49-7)39(4,52-10)33(50-8)36(53-14)54-19-13-37(2,48)24(34(47)51-9)15-11-16-21(27(43)20(15)19)28(44)22-18(41)12-17-30(23(22)26(16)42)55-35-29(45)25(40(5)6)31(46)38(17,3)56-35/h11-12,14,19,24-25,29,31-33,35-36,41,43,45-46,48H,13H2,1-10H3/t14-,19-,24-,25-,29-,31+,32-,33-,35+,36-,37-,38+,39+/m0/s1 Key: KGTDRFCXGRULNK-JYOBTZKQBE
SMILES C[C@H]1[C@@H]([C@@]([C@H]([C@@H](O1)O[C@H]2C[C@]([C@@H](C3=CC4=C(C(=C23)O)C(=O)C5=C(C=C6C(=C5C4=O)O[C@H]7[C@H]([C@@H]([C@H]([C@@]6(O7)C)O)N(C)C)O)O)C(=O)OC)(C)O)OC)(C)OC)OC
Properties
Chemical formula	C₃₉H₄₉NO₁₆
Molar mass	787.80 g/mol
Hazards
Main hazards	cardiotoxic
Related compounds
Related compounds	menogaril
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Nogalamycin is an anthracycline antibiotic produced by soil bacteria Streptomyces nogalater. It has antitumor properties but it is also highly cardiotoxic. Less cardiotoxic semisynthetic analog menogaril was developed in the 1970s. Currently nogalamycin or menogaril aren't used clinically.^[1]

References

↑ NOGALAMYCIN. ChemicalBook.com. Accessed November 28, 2012.

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