Nebacumab

Nebacumab
Monoclonal antibody
Type Whole antibody
Source Human
Target endotoxin
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 138661-01-5 N
ATC code J06BC01
ChemSpider none
KEGG D05126 YesY
 NYesY (what is this?)  (verify)

Nebacumab is a human monoclonal antibody developed for the treatment of sepsis.[1] It has been withdrawn in 1993 because it failed to reduce mortality in clinical trials.[2]

References

  1. Derkx, B.; Wittes, J.; McCloskey, R. (1999). "Randomized, Placebo‐Controlled Trial of HA‐1A, a Human Monoclonal Antibody to Endotoxin, in Children with Meningococcal Septic Shock". Clinical Infectious Diseases 28 (4): 770–726. doi:10.1086/515184. PMID 10825037.
  2. WHO: Consolidated List of Products


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