Nebacumab

Nebacumab
Monoclonal antibody
Type	Whole antibody
Source	Human
Target	endotoxin
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	138661-01-5^N
ATC code	J06BC01
ChemSpider	none
KEGG	D05126^Y

^NY (what is this?) (verify)

Nebacumab is a human monoclonal antibody developed for the treatment of sepsis.^[1] It has been withdrawn in 1993 because it failed to reduce mortality in clinical trials.^[2]

References

↑ Derkx, B.; Wittes, J.; McCloskey, R. (1999). "Randomized, Placebo‐Controlled Trial of HA‐1A, a Human Monoclonal Antibody to Endotoxin, in Children with Meningococcal Septic Shock". Clinical Infectious Diseases 28 (4): 770–726. doi:10.1086/515184. PMID 10825037.
↑ WHO: Consolidated List of Products

Monoclonal antibodies for infectious disease and toxins

Fungal ("-fung-")

Human ("-fungu-")	Efungumab

Viral ("-v(i)[r]-")

Human ("-viru-")	Diridavumab Exbivirumab Foravirumab Libivirumab Rafivirumab Regavirumab Sevirumab Tuvirumab

Humanized ("-vizu-")	Felvizumab Motavizumab Palivizumab Suvizumab

Bacterial ("-ba(c)-")

Human ("-bacu-")	Nebacumab Panobacumab Raxibacumab

Mouse ("-baco-")	Edobacomab

Chimeric ("-baxi-")	Pagibaximab

Humanized ("-bazu-")	Tefibazumab^†

Toxin ("-tox(a)-")

Human ("-toxu-")	Actoxumab Bezlotoxumab

Chimeric ("-toxaxi-")	Obiltoxaximab

Humanized ("-toxazu-")	Urtoxazumab

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Immune sera and immunoglobulins (J06)

Polyclonal antibodies

IVIG	Anthrax immune globulin Rho(D) immune globulin Hepatitis B immune globulin Zoster-immune globulin

Antiserum	Antivenom

Monoclonal antibodies

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