Nazneen Rahman

Nazneen Rahman
Nationality British
Alma mater
Thesis Localisation and characterisation of the familial tumour gene, FWT1 (1999)
Doctoral advisor Michael Stratton[1]
Notable awards FMedSci[2]
Website
www.icr.ac.uk/our-research/researchers-and-teams/professor-nazneen-rahman

Professor Nazneen Rahman FMedSci[2] is a geneticist who specialises in cancer research[3] and head of Genetics and Epidemiology at the Institute of Cancer Research.[4][5]

Education

Rahman qualified in medicine from University of Oxford in 1991, and completed a PhD in Molecular Genetics in 1999 on the Wilms' tumor susceptibility gene FWT1.[6][7] She completed her Certificate of Completion of Specialist Training in Clinical Genetics in 2001.

Career and Research

She is head of Genetics and Epidemiology at the Institute of Cancer Research, based at the Sir Richard Doll Building in Sutton. She specialises in research into the genetic mechanisms that cause cancer, particularly among groups with a predisposition to paediatric cancers or breast cancer. Through her research, Professor Rahman has provided improved screening and treatment options for NHS patients, and also provides advice on rare cancer genetics to clinicians internationally.[8] She blogs about her work at Harvesting the Genome.[9]

Rahman has a clinical role as head of the cancer genetics service at The Royal Marsden and St George’s Hospital in south west London.[1]

Awards and honours

She was elected a Fellow of the Academy of Medical Sciences in 2010. Her nomination reads:

Nazneen Rahman is Professor of Human Genetics at the Institute of Cancer Research and Head of the Clinical Genetics Department at the Royal Marsden Hospital. Her research work has been directed towards the mapping, identification and clinical characterisation of human disease genes using genome-wide linkage analysis, positional cloning, candidate gene resequencing, genome-wide association analyses and epigenetic assays. Her primary areas of research are breast cancer susceptibility, childhood cancer susceptibility and human growth disorders. In her relatively short career to date she has already identified and characterised 4 breast cancer predisposition genes and two childhood cancer predisposition genes and two overgrowth genes.[2]

In April 2014, she was named as Britain's third most influential woman in the BBC Woman's Hour power list 2014.[10]

Personal life

Rahman is also a singer-songwriter, planning to release an album in 2014.[11]

References

  1. 1 2 "Royal Marsden: Professor Nazneen Rahman". Archived from the original on 2015-02-02.
  2. 1 2 3 "Professor Nazneen Rahman FMedSci". London: The Academy of Medical Sciences. Archived from the original on 2014-05-06.
  3. Futreal, P. A.; Coin, L; Marshall, M; Down, T; Hubbard, T; Wooster, R; Rahman, N; Stratton, M. R. (2004). "A census of human cancer genes". Nature Reviews Cancer 4 (3): 177–83. doi:10.1038/nrc1299. PMC 2665285. PMID 14993899.
  4. Burton, P. R.; Clayton, D. G.; Cardon, L. R.; Craddock, N.; Deloukas, P.; Duncanson, A.; Kwiatkowski, D. P.; McCarthy, M. I.; Ouwehand, W. H.; Samani, N. J.; Todd, J. A.; Donnelly, P.; Barrett, J. C.; Burton, P. R.; Davison, D.; Donnelly, P.; Easton, D.; Evans, D.; Leung, H. T.; Marchini, J. L.; Morris, A. P.; Spencer, C. C. A.; Tobin, M. D.; Cardon, L. R.; Clayton, D. G.; Attwood, A. P.; Boorman, J. P.; Cant, B.; Everson, U.; Hussey, J. M. (2007). "Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls". Nature 447 (7145): 661–678. doi:10.1038/nature05911. PMC 2719288. PMID 17554300.
  5. Easton, D. F.; Pooley, K. A.; Dunning, A. M.; Pharoah, P. D.; Thompson, D; Ballinger, D. G.; Struewing, J. P.; Morrison, J; Field, H; Luben, R; Wareham, N; Ahmed, S; Healey, C. S.; Bowman, R; Search, Collaborators; Meyer, K. B.; Haiman, C. A.; Kolonel, L. K.; Henderson, B. E.; Le Marchand, L; Brennan, P; Sangrajrang, S; Gaborieau, V; Odefrey, F; Shen, C. Y.; Wu, P. E.; Wang, H. C.; Eccles, D; Evans, D. G.; et al. (2007). "Genome-wide association study identifies novel breast cancer susceptibility loci". Nature 447 (7148): 1087–93. doi:10.1038/nature05887. PMC 2714974. PMID 17529967.
  6. Rahman, N; Arbour, L; Tonin, P; Renshaw, J; Pelletier, J; Baruchel, S; Pritchard-Jones, K; Stratton, M. R.; Narod, S. A. (1996). "Evidence for a familial Wilms' tumour gene (FWT1) on chromosome 17q12-q21". Nature Genetics 13 (4): 461–3. doi:10.1038/ng0896-461. PMID 8696342.
  7. Rahman, N; Abidi, F; Ford, D; Arbour, L; Rapley, E; Tonin, P; Barton, D; Batcup, G; Berry, J; Cotter, F; Davison, V; Gerrard, M; Gray, E; Grundy, R; Hanafy, M; King, D; Lewis, I; Ridolfi Luethy, A; Madlensky, L; Mann, J; O'Meara, A; Oakhill, T; Skolnick, M; Strong, L; Stratton, M. R. (1998). "Confirmation of FWT1 as a Wilms' tumour susceptibility gene and phenotypic characteristics of Wilms' tumour attributable to FWT1". Human Genetics 103 (5): 547–56. doi:10.1007/pl00008708. PMID 9860296.
  8. "Institute of Cancer Research: Professor Nazneen Rahman". Archived from the original on 2014-08-25.
  9. "Harvesting the genome".
  10. "Woman's Hour Power List 2014 – Game Changers". BBC Radio 4.
  11. "NazneenMusic". SoundCloud.
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