Narasin

Narasin
Systematic (IUPAC) name

(2R)-2-[(2R,3S,5S,6R)-6-[(1S,2S,3S,5R)-5- [(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5⁷.3⁵]pentadec-13-en-9-yl]-2-hydroxy-1,3-dimethyl-4-oxoheptyl]-3,5-dimethyl-2-tetrahydropyranyl]butanoic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	55134-13-9^Y
ATCvet code	QP51AH04
PubChem	CID 65452
ChemSpider	58911
UNII	DZY9VU539P^Y
Synonyms	(4S)-4-methyl-salinomycin
Chemical data
Formula	C₄₃H₇₂O₁₁
Molar mass	765.03 g/mol
SMILES O=C([C@@H](C)[C@@H](O)[C@H](C)[C@]5([H])O[C@]([C@@H](CC)C(O)=O)([H])[C@@H](C)C[C@@H]5C)[C@H](CC)[C@@]1([H])O[C@@]2(O[C@@]3(CC[C@]([C@]4([H])O[C@@H](C)[C@@](O)(CC)CC4)(C)O3)[C@H](O)C=C2)[C@H](C)C[C@@H]1C
InChI InChI=1S/C43H72O11/c1-12-30(35(46)27(8)34(45)28(9)36-23(4)21-24(5)37(51-36)31(13-2)39(47)48)38-25(6)22-26(7)42(52-38)18-15-32(44)43(54-42)20-19-40(11,53-43)33-16-17-41(49,14-3)29(10)50-33/h15,18,23-34,36-38,44-45,49H,12-14,16-17,19-22H2,1-11H3,(H,47,48)/t23-,24-,25-,26+,27-,28-,29-,30-,31+,32+,33+,34+,36+,37+,38-,40-,41+,42-,43-/m0/s1 Key:VHKXXVVRRDYCIK-CWCPJSEDSA-N
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Narasin is a coccidiostat and antibacterial agent.^[1]^[2] It is a derivative of salinomycin with an additional methyl group.

References

↑ Gerhold, R. W.; Fuller, A. L.; Lollis, L.; Parr, C.; McDougald, L. R. (2011). "The Efficacy of Anticoccidial Products against Eimeria spp. in Northern Bobwhites". Avian Diseases 55 (1): 59–64. doi:10.1637/9572-101310-Reg.1. PMID 21500637.
↑ Fitzgerald, P. R.; Mansfield, M. E. (1989). "Effects of inoculations with Eimeria zuernii on young calves treated with decoquinate or narasin with or without dexamethasone". American journal of veterinary research 50 (7): 1056–1059. PMID 2774323.

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