NK012

NK012 is a 'nanodevice' formulation of SN-38 (an irinotecan metabolite). NK012 is an SN-38-releasing polymeric micelle constructed by covalently attaching SN-38 to the block copolymer PEG-PGlu, followed by self-assembly of amphiphilic block copolymers in aqueous media.[1] [2]

It has entered phase II clinical trials for triple-negative breast cancer and relapsed small cell lung cancer.[3]

See also

References


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