Michael M. Meguid

Michael M. Meguid, MD, Ph.D.
Born	Egypt
Residence	Syracuse, New York
Fields	obesity, neuroscience, nutrition, biochemistry
Institutions	Upstate Medical University, The State University of New York (SUNY)
Alma mater	University of London (M.D., 1968), Harvard Medical School (1972) and Massachusetts Institute of Technology (Ph.D., 1981)
Known for	Co-founder Breast Surgery Program, Upstate Medical University Editor-in-Chief, Nutrition: The International Journal of Applied and Basic Nutrition Sciences[1] Editor, [The Proceedings],[2] [The International Academy of Perinatal and Prenatal Programming] [3]
Notable awards	Recipient of American Medical Association, Joseph B. Goldberger Award in Clinical Nutrition[4] (1997) Garry/Labbe Award[5] 2010 (American Association for Clinical Chemistry) Elected Fellow 2010 European Society for Clinical Nutrition and Metabolism (ESPEN) [6]

Michael M. Meguid, MD, PhD ^[7] is Professor Surgery Emeritus at Upstate Medical University ^[8] (The State University of New York), Syracuse, New York.

Biography

Born in Egypt, Michael (Marwan) Meguid spent his childhood in Egypt, Germany, and then England. There he attended University College London (UCL) and University College Hospital Medical School, graduating with his MB BS degree in 1968. For the next two years he was an Anatomy Prosector at UCL, while he successfully completed Part 1 of the Fellowship of the Royal College of Surgeons (FRCS), London qualification. From 1970 until 1976 he did his Surgical Residency at Peter Bent Brigham Hospital, Children’s Hospital; the Joslin Clinic, Harvard Medical School; and at Boston University Hospital, Boston, Massachusetts. It was at Boston University Hospital (now Boston Medical Center^[9] that he began his surgical career in Surgical Oncology and Clinical Nutrition, as Assistant Professor. Concomitantly, from 1978 until 1982 he was a graduate student in the Department of Human Nutrition, Massachusetts Institute of Technology (MIT, Cambridge, Massachusetts, earning a PhD in Nutritional Biochemistry.

Over the next five years (1979–1984) he was Associate Surgeon at City of Hope National Medical Center, Duarte, California; UCLA Medical School; and the West Los Angeles VA Medical Center. He was founder and director of the Department of Nutrition, in the Division of Surgery, at the City of Hope. From there he was recruited to a tenured professor position at the Department of Surgery, University Hospital, Upstate Medical University, and the Syracuse VA Hospital, New York. He has been Professor of Surgery; Vice-Chair for Surgical Research; Director of Surgical Metabolism and Nutrition Laboratory, Neuroscience-Physiology Graduate Program (NIH and NGO funded continuously from 1983 through 2011), where he trained 42 graduate students and fellows; and Director of Nutritional Support Services at both hospitals. He was also the director of the Institutional Review Board at Syracuse VA Medical Center. He started in 1983 "Nutrition: The International Journal of Applied and Basic Nutritional Sciences"^[10] and in 2010 co-founded "The International Academy of Perinatal and Prenatal Programming" ^[3] with its open access e-journal "The Proceedings".^[2]

Research projects

• Optimizing the delivery of artificial nutrition to sick patients unable to sustain themselves.
• Understanding the mechanism of appetite regulation in a variety of conditions, including anorexia of cancer (he and his research team developed animal models to study anorexia of cancer and weight loss mechanisms in obesity, and reversal of Metabolic Syndrome after Roux-en-Y gastric bypass).
• Inflammatory diseases and space travel as this involves anorexia, the hypothalamus, its neurochemicals and metabolism of the GI tract.
• The influence of early life (prenatal and perinatal) programming on later health and disease as a key to understanding illnesses, and to developing drugs and treatment.

Recognitions

• Elected Fellow, International Behavioral Neuroscience Society^[11] (1997)
• Recipient of American Medical Association, Joseph B. Goldberger Award in Clinical Nutrition^[4] (1997)
• Editor – Section in Catabolism: Current Opinions in Clinical Nutrition and Metabolic Care^[12] (2001–2010)
• Promising Inventor Award, The Research Foundation, The State University of New York (2004)
• Ethan Sims Young Investigators Award^[13] Finalist, Annual NAASO Conference, Las Vegas, NV (2004)
• Who's Who in Medicine (2005–07)
• America's Top Physicians in Surgery & Research (2004–2005)
• Life Member, The Fellows Leadership Society,^[14] American College of Surgeons Foundation (2006)
• Garry/Labbe Award^[5] 2010 (American Association for Clinical Chemistry) (2010)
• Elected Fellow 2010, European Society for Clinical Nutrition and Metabolism (ESPEN) ^[6] (2010)

Scientific publication

Scopus^[15] scientific publication data for Michael M. Meguid as of January 2011:

• 353 publications
• 4485 references
• 3589 citations
• 50 book chapters
• Co-authored: McLaren DS and Meguid MM, Nutrition and its Disorders, 4th Ed., Churchill Livingstone, London, UK, 1988
• h Index: 32

Selected Examples: For these and additional works by Michael M. Meguid and colleagues, refer to PubMed.^[16]

1. Asakawa A, Inui A, Fujimiya M, Sakamaki R, Shinfuku N, Ueta Y, Meguid MM, Kasuga M. Stomach regulates energy balance via acylated ghrelin and desacyl ghrelin. 2005, Gut 54(1):18–24.
2. Giner M, Laviano A, Meguid MM, Gleason JR. In 1995 a correlation between malnutrition and poor outcome in critically ill patients still exists. 1996, Nutrition 12(1):23–29.
3. Meguid MM, Fetissov SO, Varma M, Sato T, Zhang L, Laviano A, Rossi-Fanelli, F. Hypothalamic dopamine and serotonin in the regulation of food intake. 2000, Nutrition 16(10):843–857.
4. Meguid MM, Loebl WY. Megaloblastic anemia associated with the oral contraceptive pill. 1974, Postgrad Med 50:470-472.
5. Boateng, AA, Sriram K, Meguid MM, Crook M. Refeeding Syndrome: Treatment Considerations based on Collective Analysis of Literature Case Reports. Nutrition 2010, 26(12):26.
6. Meguid, MM, Goncalves CG. Message to surgeons: the expected norm in elective complex GI cancer surgery is use of perioperative immunonutritional therapy that also saves hospital costs! 2009, Ann Surg 2493(3):64-365.
7. Guijarro A, Osei-Hyiaman D, Harvey-White J, Kunos G, Suzuki S, Nadtochiy S, Brookes PS, Meguid MM. Sustained Weight Loss after Roux-en-Y Gastric Bypass is characterized by Down Regulation of Endocannabinoids and Mitochondrial Function. 2008, Ann Surg 247(5):779-790.
8. Laviano A, Meguid MM, Inui A, Muscaritoli M, Rossi-Fanelli F. Review: Therapy insight: cancer anorecia-cachexia syndrome- when all you can eat is yourself. 2005, Nature Clinical Practice, Oncology 2:1-8.
9. Makarenko IG, Meguid MM, Gatto L, Chen C, Ramos EJ, Goncalves CG, Ugrumov MV. Normalization of hypothalamic serotonin (5-HT1B) receptor and NPY in cancer anorexia after tumor resection: An Immunocytochemical Study. 2005, Neurosci Lett 383:322-7.
10. Xu Y, Ramos EJB, Middleton F, Romanova IV, Quinn R, Chen C, Das UN, Inui A, Meguid MM. Gene expression profiles post Roux-en-Y Gastric Bypass. 2004, Surgery 136:246-52.
11. Middleton F, Ramos EJB, Xu Y, Diab H, Zhao X, Meguid MM. Application of genomic technologies: DNA-Microarrays and metabolic profiling of obesity in the hypothalamus and subcutaneous fat. 2004, Nutrition 20(1):14-25.
12. Fettisov S, Meguid MM, Sato T and Zhang L-H. Expression of dopaminergic receptors in the hypothalamus of lean and obese Zucker rats. 2002, Amer J Physiol: Reg Int & Compar Physiolol 283:R905-R910.
13. Sato T, Meguid MM, Fetissov SO, Chen C, Zhang L. Hypothalamic dopaminergic receptor expressions in anorexia of tumor bearing rats. 2001,Am J Physiol Regulatory Integrative Comp Physiol 281:R1907-R1916.

References