Semustine
Systematic (IUPAC) name | |
---|---|
N-(2-Chloroethyl)-N'-(4-methylcyclohexyl)-N-nitrosourea | |
Identifiers | |
CAS Number | 13909-09-6 |
ATC code | L01AD03 |
PubChem | CID 5198 |
ChemSpider | 5009 |
UNII | 6YY7T1T567 |
KEGG | D05822 |
ChEBI | CHEBI:6863 |
Chemical data | |
Formula | C10H18ClN3O2 |
Molar mass | 247.72 g/mol |
| |
| |
(what is this?) (verify) |
Semustine is a drug used in chemotherapy.[1] It is structurally similar to lomustine, being distinguished from it only by an additional methyl group. It has been taken off the drug market for investigation of its cancerous effects, rated as IARC Group 1 carcinogen or a known carcinogen.[2]
References
- ↑ "Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. Gastrointestinal Tumor Study Group". Journal of clinical oncology : official journal of the American Society of Clinical Oncology 10 (4): 549–557. 1992. PMID 1548520.
- ↑ http://www.cancer.org/cancer/cancercauses/othercarcinogens/generalinformationaboutcarcinogens/known-and-probable-human-carcinogens, Known and Probable Human Carcinogens, American Cancer Society
|
This article is issued from Wikipedia - version of the Friday, August 28, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.