Manidipine
 | |
| Systematic (IUPAC) name | |
|---|---|
|
2-[4-(Diphenylmethyl)piperazin-1-yl]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | |
| Clinical data | |
| Trade names | Manyper, etc. |
| AHFS/Drugs.com | International Drug Names |
| Legal status |
|
| Routes of administration | Oral |
| Identifiers | |
| CAS Number | 89226-50-6 120092-68-4 |
| ATC code | C08CA11 |
| PubChem | CID 4008 |
| ChemSpider | 3868 |
| UNII |
6O4754US88  |
| Chemical data | |
| Formula | C35H38N4O6 |
| Molar mass | 610.69 g/mol |
| |
Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.[1][2][3][4][5]
References
- ↑ Cheer, S.M.; McClellan, K. (2001), "Manidipine: A Review of its Use in Hypertension", Drugs 61 (12): 1777–99, doi:10.2165/00003495-200161120-00010, PMID 11693466, retrieved 2009-06-20
- ↑ McKeage, K.; Scott, L.J. (2004), "Manidipine: A Review of its Use in the Management of Hypertension", Drugs 64 (17): 1923–40, doi:10.2165/00003495-200464170-00011, PMID 15329044, retrieved 2009-06-20
- ↑ Roca-cusachs, A.; Triposkiadis, F. (2005), "Antihypertensive Effect of Manidipine", Drugs 65: 11–9, doi:10.2165/00003495-200565002-00003, PMID 16398058, retrieved 2009-06-20
- ↑ Otero, M.L. (2007), "Manidipine–delapril combination in the management of hypertension", Vascular Health and Risk Management 3 (3): 255–63, PMC 2293964, PMID 17703633
- ↑ Mizuno, Kenji; Haga, Hiroshi; Takahashi, Michihiko; Fukuchi, Soitsu (August 1992), "Evaluation of manidipine hydrochloride, a new calcium antagonist, in the treatment of hypertensive patients with renal disorders", Current Therapeutic Research 52 (2): 248–253, doi:10.1016/S0011-393X(05)80475-8, retrieved 2009-06-20
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