Lycopene epsilon-cyclase

Lycopene epsilon-cyclase
Identifiers
EC number 5.5.1.18
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Lycopene epsilon-cyclase (EC 5.5.1.18, CrtL-e, LCYe) is an enzyme with system name carotenoid psi-end group lyase (decyclizing).[1][2] This enzyme catalyses the following chemical reaction

carotenoid psi-end group \rightleftharpoons carotenoid epsilon-end group

The carotenoid lycopene has the psi-end group at both ends.

References

  1. Cunningham, F.X., Jr. and Gantt, E. (2001). "One ring or two? Determination of ring number in carotenoids by lycopene ε-cyclases". Proc. Natl. Acad. Sci. USA 98: 2905–2910. doi:10.1073/pnas.051618398. PMC 30238. PMID 11226339.
  2. Stickforth, P., Steiger, S., Hess, W.R. and Sandmann, G. (2003). "A novel type of lycopene ε-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4". Arch. Microbiol. 179 (6): 409–415. doi:10.1007/s00203-003-0545-4. PMID 12712234.

External links

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