Lycopene beta-cyclase

Lycopene beta-cyclase
Identifiers
EC number 5.5.1.19
CAS number 220801-82-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Lycopene beta-cyclase (EC 5.5.1.19, CrtL, CrtL-b, CrtY) is an enzyme with system name carotenoid beta-end group lyase (decyclizing).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction

carotenoid psi-end group \rightleftharpoons carotenoid beta-end group

This enzyme requires NAD(P)H.

References

  1. ↑ Cunningham, F.X., Jr., Chamovitz, D., Misawa, N., Gantt, E. and Hirschberg, J. (1993). "Cloning and functional expression in Escherichia coli of a cyanobacterial gene for lycopene cyclase, the enzyme that catalyzes the biosynthesis of β-carotene". FEBS Lett. 328: 130–138. doi:10.1016/0014-5793(93)80980-9. PMID 8344419.
  2. ↑ Cunningham, F.X., Jr., Sun, Z., Chamovitz, D., Hirschberg, J. and Gantt, E. (1994). "Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942". Plant Cell 6: 1107–1121. doi:10.2307/3869889. PMID 7919981.
  3. ↑ Hugueney, P., Badillo, A., Chen, H.C., Klein, A., Hirschberg, J., Camara, B. and Kuntz, M. (1995). "Metabolism of cyclic carotenoids: a model for the alteration of this biosynthetic pathway in Capsicum annuum chromoplasts". Plant J. 8: 417–424. doi:10.1046/j.1365-313x.1995.08030417.x. PMID 7550379.
  4. ↑ Pecker, I., Gabbay, R., Cunningham, F.X., Jr. and Hirschberg, J. (1996). "Cloning and characterization of the cDNA for lycopene β-cyclase from tomato reveals decrease in its expression during fruit ripening". Plant Mol. Biol. 30: 807–819. doi:10.1007/bf00019013. PMID 8624411.
  5. ↑ Hornero-Mendez, D. and Britton, G. (2002). "Involvement of NADPH in the cyclization reaction of carotenoid biosynthesis". FEBS Lett. 515: 133–136. doi:10.1016/s0014-5793(02)02453-5. PMID 11943208.
  6. ↑ Maresca, J.A., Graham, J.E., Wu, M., Eisen, J.A. and Bryant, D.A. (2007). "Identification of a fourth family of lycopene cyclases in photosynthetic bacteria". Proc. Natl. Acad. Sci. USA 104: 11784–11789. doi:10.1073/pnas.0702984104. PMID 17606904.

External links

This article is issued from Wikipedia - version of the Sunday, February 07, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.