Loracarbef

Loracarbef
Systematic (IUPAC) name
(6R,7S)-7-[[(2S)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
Trade names Lorabid
AHFS/Drugs.com monograph
MedlinePlus a601206
Pharmacokinetic data
Protein binding 25%
Identifiers
CAS Number 76470-66-1 YesY
ATC code J01DC08
PubChem CID 5284584
DrugBank DB00447 YesY
ChemSpider 4447634 YesY
UNII W72I5ZT78Z N
KEGG D08143 YesY
ChEMBL CHEMBL1013 N
Chemical data
Formula C16H16ClN3O4
Molar mass 349.769 g/mol
 NYesY (what is this?)  (verify)

Loracarbef is an antibiotic.[1] It is a carbacephem, but it is sometimes grouped together with the second-generation cephalosporin antibiotics. Loracarbef is a synthetic "carba" analog of cefaclor, and is more stable chemically.

History

Loracarbef received FDA approval in 1991 and it was marketed under the trade name Lorabid. Its use was discontinued in 2006.

Side effects

Diarrhea is the most common adverse effect with loracarbef. Side effects are more frequently seen with children under the age of twelve.

References

External links

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