List of unsolved problems in biology

This article lists currently unsolved problems in biology.

Problems

Adaptation At present there is no theoretical model for how adaptation occurs that is close to being complete. Mathematical models of evolution (e.g. within population genetics) describe how the process of natural selection influences the frequency of already-existing gene variants based on their relative fitnesses. Only a small amount of theory treats the problem of modelling the generation of new variants through mutation, in terms of either the fitnesses or phenotypic forms they confer.
Alkaloids The function of these substances in living organisms which produce them is not known[1]
Arthropod head problem A long-standing zoological dispute concerning the segmental composition of the heads of the various arthropod groups, and how they are evolutionarily related to each other.
Basking shark Only the right ovary in this fish appears to function, the reason is unknown.
Biological aging There are a number of hypotheses why senescence occurs including those that it is programmed by gene expression changes and that it is the accumulative damage of biological processes.
Blue Whale There is not much data on the sexuality of the biggest animal ever.[2]
Botany/Plants What is the exact evolutionary history of flowers and their blossoms?
Butterfly migration How do the descendants of Monarch butterfly all over Canada and the US eventually, after migrating for several generations, manage to return to a few relatively small overwintering spots?
Cambrian explosion What is the cause of the apparent rapid diversification of multicellular animal life around the beginning of the Cambrian, resulting in the emergence of almost all modern animal phyla?
Consciousness What is the brain basis of subjective experience, cognition, wakefulness, alertness, arousal, and attention? Is there a "hard problem of consciousness"? If so, how is it solved? What, if any, is the function of consciousness?[3][4]
Evolution of sex What selective advantages drove the development of sexual reproduction, and how did it develop?[5]
Extraterrestrial life Might life which does not originate from planet Earth also have developed on other planets? Might this life be intelligent?
Fairy circle (Africa) There is intense debate about the formation process of the circles. Research has shown that some can be explained by the activities of the sand termite, Psammotermes allocerus but there is no theory explaining all fairy circles.
Gall wasp It is largely unknown how these insects induce gall formation in plants; chemical, mechanical, and viral triggers have been discussed.
Glycogen body The function of this structure is not known.
Golgi apparatus In cell theory, what is the exact transport mechanism by which proteins travel through the Golgi apparatus?
Hammerhead shark The reason for their distinctive and unusual head structure is not known.
Homing (biology) A satisfactory explanation for the neurobiological mechanisms that allow Homing, has yet to be found.
Korarchaeota Their metabolic processes are so far unclear.
Latitudinal diversity gradient Why does biodiversity increase when going from the poles towards the equator?
Loricifera There are at least 100 species of this phylum that are yet to be described, but none of them is known to be present in the fossil record.
Origin of life Exactly how and when did life on Earth originate? Which, if any, of the many hypotheses is correct?
Paradox of the plankton The high diversity of phytoplankton seems to violate the competitive exclusion principle.

References

  1. Aniszewski, p. 142
  2. Articleworld.org Blue Whale
  3. Sejnowski, Terrence J.; Hemmen, J. L. van (2006). 23 problems in systems neuroscience (PDF). Oxford [Oxfordshire]: Oxford University Press. ISBN 0-19-514822-3.
  4. Tononi, G; Koch, C. (2015). "Consciousness: Here, there and everywhere?" (PDF). Philosophical Transactions of the Royal Society London B.
  5. Thomas N. Sherratt, David M. Wilkinson. Big questions in ecology and evolution. Oxford University Press US, 2009. ISBN 978-0-19-954861-3

See also

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