Leukotriene D4

Leukotriene D4
Identifiers
73836-78-9 YesY
ChEBI CHEBI:28666 N
ChEMBL ChEMBL288943 N
Jmol interactive 3D Image
MeSH Leukotriene+D4
PubChem 5280878
Properties
C25H40N2O6S
Molar mass 496.661 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Leukotriene D4 (LTD4) is one of the leukotrienes. Its function main in the body is to induce the contraction of smooth muscle, resulting in bronchoconstriction and vasoconstriction. It also increases vascular permeability. LTD-4 is released by basophils. Other leukotrienes that function in a similar manner are leukotrienes C4 and E4. Pharmacological agents that inhibit the function of these leukotrienes are leukotriene receptor antagonists (e.g. Zafirlukast, montelukast) and are useful for asthmatic individuals.

Eicosanoid synthesis. (Leukotrienes at right.)

References



    This article is issued from Wikipedia - version of the Tuesday, July 07, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.