John O'Keefe

John O'Keefe may refer to:

• John O'Keeffe (Irish writer) (1747–1833), sometimes O'Keefe, Irish playwright
• John O'Keeffe (Irish painter) (c. 1797–1838), Irish painter
• John O'Keeffe (politician), Member of Parliament for Dungarvan, 1874–1877
• John O'Keefe (Australian politician) (1880–1942), Queensland state MP
• John O'Keeffe (Cork hurler), Irish hurler in the 1910s and 20s
• Jack O'Keefe (1915–2000), Australian rules footballer
• John A. O'Keefe (1916–2000), American planetary scientist
• Johnny O'Keefe (1935–1978), Australian rock and roll singer
• John O'Keefe (neuroscientist) (born 1939), American British neuroscientist, 2014 Nobel Prize laureate in Physiology or Medicine
• John O'Keefe (playwright) (born 1940), American playwright
• John Martin O'Keefe (born 1946), U.S. diplomat
• John O'Keeffe (Gaelic footballer) (born 1951), Irish footballer who played for Kerry
• John O'Keeffe (Tipperary hurler) (born 1988), Irish hurler in the 2000s