Isomigrastatin

Isomigrastatin
Names

IUPAC name 4-[7-(4-Hydroxy-5-methoxy-3-methyl-12-oxo-oxacyclododeca-6,10-dien-2-yl)-5-methyl-4-oxo-oct-6-enyl]-piperidine-2,6-dione
Identifiers
CAS Number	415952-70-4^Y
Jmol interactive 3D	Image
SMILES C[C@H]([C@H](/[C@@](C)=C/[C@@H](C(CCCC2CC(NC(C2)=O)=O)=O)C)O1)[C@H](O)[C@@H](OC)/C=C/CC/C=C/C1=O
Properties
Chemical formula	C₂₇H₃₉NO₇
Molar mass	489.60 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is ^YN ?)
Infobox references

Isomigrastatin is an analogue of migrastatin, an organic compound that naturally occurs in the Streptomyces platensis bacteria. Isomigrastatin has shown promise as a drug in the treatment of cancer. A laboratory synthesis was reported in 2007.^[1]

References

↑ Krauss, IJ; et al. (2007). "Total Synthesis of (+)-Isomigrastatin". Angewandte Chemie 46 (29): 5576–5579. doi:10.1002/anie.200701837. PMID 17583888.

This article is issued from Wikipedia - version of the Tuesday, September 01, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.