Diodone

Diodone
Systematic (IUPAC) name

(3,5-Diiodo-4-oxo-1(4H)-pyridinyl)acetic acid
Identifiers
ATC code	V08AA10
PubChem	CID 9304
ChemSpider	8945
Synonyms	Iodopyracet, pelvirinic acid, umbradilic acid
Chemical data
Formula	C₇H₅I₂NO₃
Molar mass	404.928 g/mol
SMILES O=C(O)CN/1/C=C(/I)C(=O)C(\I)=C\1
InChI InChI=1S/C7H5I2NO3/c8-4-1-10(3-6(11)12)2-5(9)7(4)13/h1-2H,3H2,(H,11,12) Key:PVBALTLWZVEAIO-UHFFFAOYSA-N

Diodone is a radiocontrast agent used in urography.^[1] It is usually formulated as a salt with diethanolamine.

References

↑ Wilson, DM; Apter, JT; Schwartz, FD (1970). "A model for measuring renal blood flow from plasma disappearance of iodopyracet". Journal of Applied Physiology 28 (1): 79–88. doi:10.1007/BF00698048. PMID 5409794.

Contrast media (V08)

X-ray and CT

Iodinated,
Water soluble

Nephrotropic, high osmolar	Diatrizoic acid^# Metrizoic acid Iodamide Iotalamic acid Ioxitalamic acid Ioglicic acid Acetrizoic acid Iocarmic acid Methiodal Diodone

Nephrotropic, low osmolar	Metrizamide Iohexol^# Ioxaglic acid Iopamidol Iopromide Iotrolan Ioversol Iopentol Iodixanol Iomeprol Iobitridol Ioxilan

Hepatotropic	Iodoxamic acid Iotroxic acid Ioglycamic acid Adipiodone Iobenzamic acid Iopanoic acid Iocetamic acid Sodium iopodate Tyropanoic acid Calcium iopodate

Iodinated,
Water insoluble

Non-iodinated

Barium sulfate^#

MRI

Paramagnetic	Gadolinium-based: Gadobenic acid Gadobutrol Gadodiamide Gadofosveset Gadolinium Gadopentetic acid Gadoteric acid Gadoteridol Gadoversetamide Gadoxetic acid Other: Ferric ammonium citrate Mangafodipir

Superparamagnetic	Ferumoxsil Ferristene Iron oxide, nanoparticles

Other	Perflubron

Ultrasound

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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