INSL5
| Insulin-like 5 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | INSL5 ; PRO182; UNQ156 | ||||||||||||
| External IDs | OMIM: 606413 MGI: 1346085 HomoloGene: 48350 GeneCards: INSL5 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10022 | 23919 | |||||||||||
| Ensembl | ENSG00000172410 | ENSMUSG00000066090 | |||||||||||
| UniProt | Q9Y5Q6 | Q9WUG6 | |||||||||||
| RefSeq (mRNA) | NM_005478 | NM_001290648 | |||||||||||
| RefSeq (protein) | NP_005469 | NP_001277577 | |||||||||||
| Location (UCSC) |
Chr 1: 66.8 – 66.8 Mb |
Chr 4: 103.02 – 103.03 Mb | |||||||||||
| PubMed search | |||||||||||||
Insulin-like peptide INSL5 is a protein that in humans is encoded by the INSL5 gene.[1][2]
The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7).[2]
References
- ↑ Conklin D, Lofton-Day CE, Haldeman BA, Ching A, Whitmore TE, Lok S, Jaspers S (Sep 1999). "Identification of INSL5, a new member of the insulin superfamily". Genomics 60 (1): 50–6. doi:10.1006/geno.1999.5899. PMID 10458910.
- 1 2 "Entrez Gene: INSL5 insulin-like 5".
Further reading
- Liu C, Kuei C, Sutton S, et al. (2005). "INSL5 is a high affinity specific agonist for GPCR142 (GPR100)". J. Biol. Chem. 280 (1): 292–300. doi:10.1074/jbc.M409916200. PMID 15525639.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Koman A, Cazaubon S, Couraud PO, et al. (1996). "Molecular characterization and in vitro biological activity of placentin, a new member of the insulin gene family". J. Biol. Chem. 271 (34): 20238–41. doi:10.1074/jbc.271.34.20238. PMID 8702754.
External links
- INSL5 human gene location in the UCSC Genome Browser.
- INSL5 human gene details in the UCSC Genome Browser.
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