Hfq binding sRNA

isrA Hfq binding RNA
Predicted secondary structure of isrA Hfq binding RNA
Identifiers
Symbol	isrA
Rfam	RF01385
Other data
RNA type	gene, sRNA
Domain(s)	Enterobacteriaceae

Hfq protein from S. aureus with a bound sRNA.

A Hfq binding sRNA is an sRNA that binds the bacterial RNA binding protein called Hfq. A number of bacterial small RNAs which have been shown to bind to Hfq have been characterised (see list). Many of these RNAs share a similar structure composed of three stem-loops.^[1] Recent studies have expanded this list and experimentally validated a total of 64 Hfq binding sRNA in Salmonella Typhimurium.^[2][3][4] Genomic SELEX has been used to show that Hfq binding RNAs are enriched in the sequence motif 5'-AAYAAYAA-3'.^[5]

Bacterial Hfq binding sRNAs

References

Further reading

External links

• Rfam database

Gallery of secondary structure images isrA Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01385.  isrB Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01386.  isrC Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01387.  isrD Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01388.  isrF Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01389.  isrG Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01390.  isrH Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01391.  isrI Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01392.  isrJ Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01393.  isrK Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01394.  isrL Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01395.  isrN Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01396.  isrO Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01397.  isrP Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01398.  isrQ Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01399.  istR Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01400.  rseX Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01401.  STnc150 Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01402.  STnc290 Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01403.  STnc440 Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01404.  STnc490k Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01405.  STnc500 Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01406.  STnc560 Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01407.  sraL Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01408.  STnc250 Hfq binding RNA: Predicted secondary structure taken from the Rfam database. Family RF01409.