Hemin

For the given name, see Hemin (given name).
Hemin
Systematic (IUPAC) name
Chloro[3,7,12,17-tetramethyl-8,13-divinylporphyrin-2,18-dipropanoato(2−)]iron(III)
Clinical data
AHFS/Drugs.com Consumer Drug Information
Pregnancy
category
  • US: C (Risk not ruled out)
Legal status
Routes of
administration
Intravenous infusion
Identifiers
CAS Number 16009-13-5 YesY
ATC code B06AB01
PubChem CID 5318002
ChemSpider 21160444 YesY
UNII 743LRP9S7N YesY
ChEMBL CHEMBL1628226 N
Chemical data
Formula C34H32ClFeN4O4
Molar mass 651.94 g/mol
 NYesY (what is this?)  (verify)

Hemin (trade name Panhematin) is an iron-containing porphyrin.[1] More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.

It is used in the management of porphyria attacks, particularly in acute intermittent porphyria.

It is sometimes distinguished from hematin which has a hydroxide ligand in place of the chloride. However, the terms are sometimes equated.[2]

Hematin is considered the "X factor" required for the growth of Haemophilus influenzae.[3]

See also

References

  1. "hemin" at Dorland's Medical Dictionary
  2. "hematin" at Dorland's Medical Dictionary
  3. Sherris, John C.; Ryan, Kenneth J.; Ray, C. L. (2004). Sherris medical microbiology: an introduction to infectious diseases. New York: McGraw-Hill. p. 395. ISBN 0-8385-8529-9.

External links

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