HLA-B67

major histocompatibility complex (human), class I, B67
Alleles B*6701
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*6701
Locus chr.6 6p21.31

HLA-B67 (B67) is an HLA-B serotype. The serotype identifies the more common HLA-B*67 gene products.[1] B67 is region specific recombinant haplotype formed by the gene conversion of B*39, an allele common along the Northwest Pacific Rim (Taiwan, Japan, Korea, Coastal Siberia), and B7, B22, or B27.[2] (For terminology help see: HLA-serotype tutorial)

Serotype

B67 Serotype recognition of the B*67 allele-group gene products[3]
B*67 B67 Other Sample
allele % % size (N)
6701 32 62 81

By allele

Regions of higher B*6701 frequency
Japan
Taiwan
Heilongjiang
province, China
(Harbin city)
Beijing
China
Shandong
peninsula
HLA B*6701 frequencies
freq
ref. Population (%)
[4] Osaka Region (Japan)2.6
[4] Hakka (Taiwan)1.8
[4] Japan (5)1.7
[4] Harbin Man (China) 1.7
[4] Beijing (China)1.5
[4] Linqu (Shandong, China)1.1
[4] Siraya (Taiwan)1.0
[4] Portugal South1.0
[4] Oold (Mongolia)1.0
[4] American Samoa1.0
[4] Pazeh (Taiwan)0.9
[4] South Korea (3)0.9
[4] N. Korean (Harbin,China)0.8
[4] Arratia Basque (Spain)0.6
[4] Tarialan Khoton (Mongolia) 0.6
[4] Shanghai (China) 0.6
[4] Natal Zulu (South African)0.5
[4] Yunnan Han (China)0.5
[4] Turkey0.4
[4] Southern Han (China)0.4
[4] Tuva (Russia)0.3
[4] Chinese (Hong Kong, China)0.1

References

  1. ↑ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. ↑ Little AM, Domena JD, Hildebrand WH, et al. (1994). "HLA-B67: a member of the HLA-B16 family that expresses the ME1 epitope". Tissue Antigens 43 (1): 38–43. doi:10.1111/j.1399-0039.1994.tb02294.x. PMID 7517584.
  3. ↑ derived from IMGT/HLA
  4. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)
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