Grifolin

Grifolin
Names

IUPAC name 5-Methyl-2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]benzene-1,3-diol
Identifiers
ChEMBL	ChEMBL487804
ChemSpider	4522608
Jmol interactive 3D	Image
PubChem	5372312
InChI InChI=1S/C22H32O2/c1-16(2)8-6-9-17(3)10-7-11-18(4)12-13-20-21(23)14-19(5)15-22(20)24/h8,10,12,14-15,23-24H,6-7,9,11,13H2,1-5H3/b17-10+,18-12+ Key: PZHNKNRPGLTZPO-VZRGJMDUSA-N InChI=1/C22H32O2/c1-16(2)8-6-9-17(3)10-7-11-18(4)12-13-20-21(23)14-19(5)15-22(20)24/h8,10,12,14-15,23-24H,6-7,9,11,13H2,1-5H3/b17-10+,18-12+ Key: PZHNKNRPGLTZPO-VZRGJMDUBE
SMILES CC1=CC(=C(C(=C1)O)C/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)O
Properties
Chemical formula	C₂₂H₃₂O₂
Molar mass	328.50 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Grifolin is an isolate of the mushroom Albatrellus confluens which upregulates DAPK1 in vitro.^[1]

References

↑ Luo, XJ; Li, LL; Deng, QP; Yu, XF; Yang, LF; Luo, FJ; Xiao, LB; Chen, XY; Ye, M; Liu, JK; Cao, Y (2011). "Grifolin, a potent antitumour natural product upregulates death-associated protein kinase 1 DAPK1 via p53 in nasopharyngeal carcinoma cells". European journal of cancer (Oxford, England : 1990) 47 (2): 316–25. doi:10.1016/j.ejca.2010.09.021. PMID 20943371.

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