GBF1

Golgi brefeldin A resistant guanine nucleotide exchange factor 1

Identifiers

GBF1 ; ARF1GEF

External IDs

OMIM: 603698 MGI: 1861607 HomoloGene: 37897 GeneCards: GBF1 Gene

Gene ontology
Molecular function	• ARF guanyl-nucleotide exchange factor activity • protein binding • phosphatidylinositol-3,4,5-trisphosphate binding • phosphatidylinositol-3,5-bisphosphate binding
Cellular component	• Golgi membrane • mitochondrion • peroxisome • endoplasmic reticulum lumen • endoplasmic reticulum-Golgi intermediate compartment • Golgi apparatus • Golgi stack • cis-Golgi network • trans-Golgi network • lipid particle • plasma membrane • membrane • cell leading edge
Biological process	• cell activation involved in immune response • retrograde vesicle-mediated transport, Golgi to ER • post-Golgi vesicle-mediated transport • Golgi to endosome transport • organelle organization • Golgi organization • regulation of mitotic cell cycle • protein transport • viral process • regulation of cell adhesion • neutrophil chemotaxis • regulation of ARF protein signal transduction • protein localization to Golgi apparatus • retrograde transport, endosome to Golgi • positive regulation of GTPase activity • COPI coating of Golgi vesicle • membrane organization • establishment of monopolar cell polarity • protein localization to endoplasmic reticulum exit site • Golgi disassembly • endoplasmic reticulum-Golgi intermediate compartment organization • reactive oxygen species biosynthetic process • protein localization to endoplasmic reticulum tubular network • regulation of protein localization to cell surface
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 10:
102.25 – 102.38 Mb

Chr 19:
46.15 – 46.29 Mb

PubMed search

Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the GBF1 gene.^[1]^[2]

References

↑ Mansour SJ, Herbrick JA, Scherer SW, Melancon P (Jan 1999). "Human GBF1 is a ubiquitously expressed gene of the sec7 domain family mapping to 10q24". Genomics 54 (2): 323–7. doi:10.1006/geno.1998.5563. PMID 9828135.
↑ "Entrez Gene: GBF1 golgi-specific brefeldin A resistance factor 1".

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GBF1

References

Further reading