Furanylfentanyl
 | |
| Systematic (IUPAC) name | |
|---|---|
|
N-(1-(2-phenylethyl)-4-piperidinyl)-N-phenylfuran-2-carboxamide | |
| Clinical data | |
| Legal status |
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| Identifiers | |
| CAS Number | 101345-66-8 |
| ATC code | None |
| PubChem | CID 13653606 |
| ChemSpider | N/A |
| Chemical data | |
| Formula | C24H26N2O2 |
| Molar mass | 374.484 g/mol |
| |
| |
Furanylfentanyl (Fu-F) is an opioid analgesic that is an analog of fentanyl[1] and has been sold online as a designer drug.[2] It has an ED50 value of 0.02mg/kg in mice.[3]
The law in the UK would confire legal status as the catchall law defines the following '(vi) by replacement of the N-propionyl group by another acyl group'. A cycloacyl would fall outside the current law, as would any analogue with a cycloacyl group.
A closely related compound with furanylethyl replacing the phenethyl of fentanyl, rather than furanoyl replacing the propanoyl, also appears to have been sold under the same name.
Side effects
Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.[4]
Life-threatening adverse reactions have been observed.[5]
Legal status
Furanylfentanyl is illegal in Sweden as of 26. January 2016.[6]
See also
- 3-Methylbutyrfentanyl
- 3-Methylfentanyl
- 4-Fluorofentanyl
- α-Methylfentanyl
- Acetylfentanyl
- Butyrfentanyl
- List of Fentanyl analogues
- Mirfentanyl
References
- ↑ Jerome R. Bagley, Richard L. Wynn, Frieda G. Rudo, Brian M. Doorley, H. Kenneth Spencer, Theodore Spaulding (March 1989). "New 4-(heteroanilido)piperidines, structurally related to the pure opioidagonist fentanyl, with agonist and/or antagonist properties". Journal of Medicinal Chemistry 3 (2): 663–671. doi:10.1021/jm00123a028. PMID 2563773.
- ↑ "Bluelight - Novel opioid, Furanylfentanyl". Retrieved 20 June 2015.
- ↑ Bao-Shan Huang, Ross C. Terrell, Kirsten H. Deutsche, Linas V. Kudzma, Nhora L. Lalinde (22 April 1986). "Patent US 4584303 - N-aryl-N-(4-piperidinyl)amides and pharmaceutical compositions and method employing such compounds". Retrieved 1 September 2015.
- ↑ Jane Mounteney, Isabelle Giraudon, Gleb Denissov, Paul Griffiths (July 2015). "Fentanyls: Are we missing the signs? Highly potent and on the rise in Europe.". The international journal of drug policy. 26 (7): 626–631. doi:10.1016/j.drugpo.2015.04.003. PMID 25976511.
- ↑ Anders Helander, Matilda Bäckberg, Olof Beck (2016). "Intoxications involving the fentanyl analogs acetylfentanyl, 4-methoxybutyrfentanyl and furanylfentanyl: results from the Swedish STRIDA project". Clinical Toxicology. doi:10.3109/15563650.2016.1139715.
- ↑ "31 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. November 2015.