Friulimicin

Friulimicin B
Names

Other names Friulimycin B
Identifiers
CAS Number	239802-15-4
ChEMBL	ChEMBL1688547^N
Jmol interactive 3D	Image
PubChem	56842195
InChI InChI=1S/C59H94N14O19/c1-30(2)19-14-12-10-8-9-11-13-15-22-41(75)65-35(25-40(61)74)52(84)71-49-34(7)64-53(85)39-21-18-24-73(39)57(89)46(31(3)4)69-56(88)48(33(6)60)68-43(77)29-63-50(82)36(26-44(78)79)66-42(76)28-62-51(83)37(27-45(80)81)67-55(87)47(32(5)59(91)92)70-54(86)38-20-16-17-23-72(38)58(49)90/h13,15,30-39,46-49H,8-12,14,16-29,60H2,1-7H3,(H2,61,74)(H,62,83)(H,63,82)(H,64,85)(H,65,75)(H,66,76)(H,67,87)(H,68,77)(H,69,88)(H,70,86)(H,71,84)(H,78,79)(H,80,81)(H,91,92)/b15-13-/t32-,33+,34-,35-,36-,37-,38+,39-,46-,47-,48+,49-/m0/s1 Key: HVYFVLAUKMGKHL-USKUEUQVSA-N
SMILES C[C@H]1[C@@H](C(=O)N2CCCC[C@@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)N1)C(C)C)[C@@H](C)N)CC(=O)O)CC(=O)O)[C@H](C)C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)C/C=C\CCCCCCCC(C)C
Properties
Chemical formula	C₅₉H₉₄N₁₄O₁₉
Molar mass	1,303.48 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Friulimicin B is a lipopeptide antibiotic produced by Actinoplanes friuliensis. It includes the unusual amino acid methylaspartate.^[1]

References

↑ Heinzelmann, E.; Berger, S.; Puk, O.; Reichenstein, B.; Wohlleben, W.; Schwartz, D. (2003). "A Glutamate Mutase is Involved in the Biosynthesis of the Lipopeptide Antibiotic Friulimicin in Actinoplanes friuliensis". Antimicrobial Agents and Chemotherapy 47 (2): 447–57. doi:10.1128/AAC.47.2.447-457.2003. PMC 151761. PMID 12543643.

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