Flutrimazole

Flutrimazole
Systematic (IUPAC) name

(RS)-1-[(2-Fluorophenyl)(4-fluorophenyl)benzyl]-1H-imidazole
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	119006-77-8^Y
ATC code	D01AC16 G01AF18
PubChem	CID 3401
ChemSpider	3284^Y
UNII	776S0UP252^Y
KEGG	D07193^Y
ChEBI	CHEBI:82864^N
ChEMBL	CHEMBL2107430
Chemical data
Formula	C₂₂H₁₆F₂N₂
Molar mass	346.373 g/mol
Chirality	1 : 1 mixture (racemate)
SMILES Fc1ccc(cc1)C(c2c(F)cccc2)(c3ccccc3)n4ccnc4
InChI InChI=1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H^Y Key:QHMWCHQXCUNUAK-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Flutrimazole is a wide spectrum antifungal drug. It is used for the topical treatment of superficial mycoses of the skin. Flutrimazole is an imidazole derivative. It interferes with the synthesis of ergosterol by inhibiting the activity of the enzyme lanosterol-14-demethylase.

References

The Merck Index, 12th Edition. 4247

Gynecological anti-infectives and antiseptics (G01)

Antibiotics

Arsenic compounds

Acetarsol

Quinoline derivatives

Organic acids

Sulfonamides

Sulfatolamide

Antifungals

Imidazoles	Metronidazole Clotrimazole Miconazole Econazole Ornidazole Isoconazole Tioconazole Ketoconazole Fenticonazole Azanidazole Propenidazole Butoconazole Omoconazole Oxiconazole Flutrimazole

Triazoles	Terconazole

Polyenes	Nystatin Natamycin Amphotericin B

Other	Ciclopirox Methylrosaniline

Other

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