Flavanone

Flavanone skeleton with locants

The flavanones are a type of flavonoids. They are generally glycosylated by a disaccharide at position seven to give flavanone glycosides.

List of flavanones

Metabolism

The enzyme chalcone isomerase uses a chalcone-like compound to produce a flavanone.
Flavanone 4-reductase is an enzyme that uses (2S)-flavan-4-ol and NADP+ to produce (2S)-flavanone, NADPH, and H+.

Synthesis

Numerous methods exist for the enantioselective chemical and biochemical synthesis of flavanones and related compounds.[1]

References

  1. Nibbs, AE; Scheidt, KA (2012). "Asymmetric Methods for the Synthesis of Flavanones, Chromanones, and Azaflavanones". European journal of organic chemistry 2012 (3): 449–462. doi:10.1002/ejoc.201101228. PMC 3412359. PMID 22876166.


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