Ferruginous body

Ferruginous bodies. H&E stain.

A dy' (pl. ferruginous bodies), is a histopathologic finding in interstitial lung disease suggestive of significant asbestos exposure (asbestosis). Asbestos exposure is associated with occupations such as shipbuilding, roofing, plumbing, and construction.

They appear as small brown nodules in the septum of the alveolus. Ferruginous bodies are typically indicative of asbestos inhalation (when the presence of asbestos is verified they are called "asbestos bodies"). In this case they are fibers of asbestos coated with an iron-rich material derived from proteins such as ferritin and hemosiderin.^[1] Ferruginous bodies are believed to be formed by macrophages that have phagocytosed and attempted to digest the fibers.

Additional images

Micrograph of asbestosis with prominent ferruginous bodies. H&E stain.

References

↑ Formation of ferruginous bodies

Eponymous medical signs for circulatory system

Heart disease

Heart murmur	Systolic heart murmur: benign paediatric heart murmur (Still's murmur) Diastolic heart murmur: pulmonic regurgitation (Graham Steell murmur) aortic insufficiency (Austin Flint murmur) carey coombs murmur mitral regurgitation (Presystolic murmur)

Aortic insufficiency	Watson's water hammer pulse/Corrigan pulse De Musset's sign Duroziez's sign Müller's sign Quincke's sign Austin Flint murmur Mayne's sign

Other endocardium	endocarditis: Roth's spot Janeway lesion/Osler's node Bracht-Wachter bodies

Pericardium	cardiac tamponade/pericardial effusion: Beck's triad Ewart's sign

Other	rheumatic fever: Anitschkow cell Aschoff body EKG (Osborn wave) angina pectoris (Levine's sign) Gallavardin phenomenon

Vascular disease

Arterial	aortic aneurysm (Cardarelli's sign, Oliver's sign) pulmonary embolism (McConnell's sign) radial artery sufficiency (Allen's test) pseudohypertension (Osler's sign) thrombus (Lines of Zahn) Adson's sign arteriovenous fistula (Nicoladoni sign)

Venous	Friedreich's sign Caput medusae Kussmaul's sign DVT Bancroft's sign Homans sign Lisker's sign Louvel's sign Lowenberg's sign Peabody's sign Pratt's sign Rose's sign Trendelenburg test superior vena cava syndrome (Pemberton's sign)

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