Exoribonuclease II

Exoribonuclease II
Identifiers
EC number 3.1.13.1
CAS number 37288-24-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Exoribonuclease II (EC 3.1.13.1, ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, exoribonuclease (misleading), 5'-exoribonuclease) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates

This enzyme has preference for single-stranded RNA.

See also

References

  1. ↑ Nossal, N.G. and Singer, M. (1968). "The processive degradation of individual polyribonucleotide chains. I. Escherichia coli ribonuclease II". J. Biol. Chem. 243: 913–922. PMID 4867942.
  2. ↑ Schmidt, F.J. and McClain, W.H. (1978). "An Escherichia coli ribonuclease which removes an extra nucleotide from a biosynthetic intermediate of bacteriophage T4 proline transfer RNA". Nucleic Acids Res. 5: 4129–4139. doi:10.1093/nar/5.11.4129. PMID 364422.
  3. ↑ Shimura, Y., Sakano, H. and Nagawa, F. (1978). "Specific ribonucleases involved in processing of tRNA precursors of Escherichia coli. Partial purification and some properties". Eur. J. Biochem. 86: 267–281. doi:10.1111/j.1432-1033.1978.tb12308.x. PMID 350582.
  4. ↑ Sporn, M.B., Lazarus, H.M. Smith, J.M. and Henderson, W.R. (1969). "Studies on nuclear exoribonucleases. 3. Isolation and properties of the enzyme from normal and malignant tissues of the mouse". Biochemistry 8: 1698–1706. doi:10.1021/bi00832a053. PMID 5805304.

External links

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