Palmar erythema
| Palmar erythema | |
|---|---|
| Classification and external resources | |
| Specialty | dermatology |
| ICD-10 | L53.8 (ILDS L53.840) |
| ICD-9-CM | 695.0 |
| DiseasesDB | 24070 |
Palmar erythema is reddening of the palms at the thenar and hypothenar eminences.[1]:139
Causes
It is associated with various physiological as well as pathological changes, or may be a normal finding:
- Portal hypertension
- Chronic liver disease (including chronic hepatitis[2])
- Pregnancy
- Polycythemia
- Thyrotoxicosis
- Rheumatoid arthritis (especially in patients with polycythaemia)[3]
- Eczema and psoriasis
- Deep telangiectasias
- Coxsackievirus A infection (Hand, foot and mouth disease)[4]
- Rocky Mountain spotted fever[4]
- Secondary syphilis[4]
- Kawasaki disease
- Adverse drug reaction: palmoplantar erythrodysesthesia (acral erythema)
Because circulating levels of estrogen increase in both cirrhosis and pregnancy, estrogen was thought to be the cause for the increased vascularity. More recently, nitric oxide has been implicated in the pathogenesis of palmar erythema.
See also
References
- ↑ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
- ↑ Basic pathology 8th edition p 646
- ↑ Saario R, Kalliomaki JL (Dec 1985), "Palmar erythema in rheumatoid arthritis", Clin Rheumatol. 4 (4), pp. 449–51, doi:10.1007/BF02031898, PMID 3830522
- 1 2 3 Le T, Bhushan V, Vasan N (2010), First Aid for the USMLE Step 1, p. 156, mhid: 0-07-163340
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