Encenicline
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| Systematic (IUPAC) name | |
|---|---|
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N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-7-chloro-1-benzothiophene-2-carboxamide | |
| Identifiers | |
| CAS Number | 550999-75-2 |
| ATC code | None |
| PubChem | CID 46196517 |
| ChemSpider | 28637768 |
| ChEMBL | CHEMBL2151572 |
| Chemical data | |
| Formula | C16H17ClN2OS |
| Molar mass | 320.837 g/mol |
| |
| |
Encenicline (INN, USAN) (code names EVP-6124, MT-4666) is a selective partial agonist of the α7 nicotinic receptor, and is in phase III clinical trials for the treatment of cognitive impairment in schizophrenia.[1][2]
See also
References
- ↑ Melville, Nancy A. "Novel Drug Targets 'Huge Unmet Need' in Schizophrenia". Medscape. Retrieved 13 April 2015.
- ↑ Barbier, AJ (2015-02-01). "Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Encenicline, a Selective α7 Nicotinic Receptor Partial Agonist, in Single Ascending-dose and Bioavailability Studies". Clinical Therapeutics 37 (2): 311–24. doi:10.1016/j.clinthera.2014.09.013. PMID 25438724.
External links
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