Distribution law

"Partition law" redirects here. For the legal term, see Partition (law).

Distribution law [1] or the Nernst's distribution law gives a generalisation which governs the distribution of a solute between two non miscible solvents.This law was first given by Nernst who studied the distribution of several solutes between different appropriate pairs of solvents.

The statement of the law is

" If a solute X distributes itself between two non miscible solvents A & B at constant temperature & X is in the same molecular condition in both the solvents, then: concentration of X in A / Concentration of X in B = Kd"

Where Kd is called the distribution coefficient or the partition coefficient.

If C1 denotes the concentration of solute in solvent A & C2, the concentration of X in B; Nernst's distribution law can be expressed as C1/C2 = Kd

See also

ITIES

References

  1. ↑ Martin's Physical Pharmacy & pharmaceutical sciences; fifth edition, Patrick.J.Sinko ISBN 0-7817-6426-2, Lippincot williams & wilkins.
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