Difetarsone
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| Systematic (IUPAC) name | |
|---|---|
|
[4-[2-[(4-arsonophenyl)amino]ethylamino]phenyl] arsonic acid | |
| Identifiers | |
| CAS Number | 3639-19-8 |
| ATC code | P01AR02 QP51AD02 |
| PubChem | CID 68199 |
| ChemSpider | 61506 |
| UNII |
G4G9J3Q65W  |
| KEGG | D07357 |
| Chemical data | |
| Formula | C14H18As2N2O6 |
| Molar mass | 460.146 g/mol |
Difetarsone is an antiprotozoal agent. Various studies have shown it to be particularly effective against Trichuris trichiura, commonly known as the whipworm. Prior to the drugs use in the early 1970s, there were few effective treatments for this infection.[1] It has also been used to treat Entamoeba histolytica infections.[2]
Difetarsone often has minor side effects, which include rashes, nausea and vomiting. It has also resulted in angioedema in at least one known case.[2]
References
- ↑ P.M. Leary; C. Jones; F. Douglas; S.T. Boyd (June 1972). "Difetarsone in Difetarsone in outpatient treatment of Trichuris trichiura infestation". Archives of Disease in Childhood 49 (6): 486–8. doi:10.1136/adc.49.6.486. PMC 1648795. PMID 4851370. Retrieved October 6, 2013.
- 1 2 Jeffrey K. Aronson (2009). Meyler's Side Effects of Antimicrobial Drugs. p. 834. ISBN 9780080932934. Retrieved October 7, 2013.
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