Dienestrol
 | |
| Systematic (IUPAC) name | |
|---|---|
|
4-[4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol; p-[(E,E)-1-Ethylidene-2-(p-hydroxyphenyl)-2-butenyl]phenol | |
| Clinical data | |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Pharmacokinetic data | |
| Protein binding | 50 to 80% |
| Identifiers | |
| CAS Number |
84-17-3  |
| ATC code | G03CB01 G03CC02 |
| PubChem | CID 667476 |
| IUPHAR/BPS | 7160 |
| DrugBank |
DB00890  |
| ChemSpider |
580857 |
| UNII |
RRW32X4U1F |
| KEGG |
D00898 |
| ChEBI |
CHEBI:4518 |
| ChEMBL |
CHEMBL1018 |
| Chemical data | |
| Formula | C18H18O2 |
| Molar mass | 266.334 g/mol |
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Dienestrol (INN, USAN) (brand names Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol, numerous others), also known as dienoestrol (BAN), is a synthetic, non-steroidal estrogen of the stilbestrol group used to treat menopausal symptoms in the United States and Europe.[1][2][3][4] It was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.[4] Dienestrol is a close analogue of diethylstilbestrol.[5]
Dienestrol diacetate (brand names Faragynol, Gynocyrol, others) also exists and is used medically.[2]
See also
References
- ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 331–. ISBN 978-3-88763-075-1.
- 1 2 J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 390–. ISBN 978-1-4757-2085-3.
- ↑ Muller (19 June 1998). European Drug Index: European Drug Registrations, Fourth Edition. CRC Press. pp. 361–. ISBN 978-3-7692-2114-5.
- 1 2 William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 1286–. ISBN 978-0-8155-1856-3.
- ↑ VITAMINS AND HORMONES. Academic Press. 1 January 1945. pp. 233–. ISBN 978-0-08-086600-0.
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