DNA damage-binding protein
| damage-specific DNA binding protein 1, 127kDa | |
|---|---|
| Identifiers | |
| Symbol | DDB1 |
| Alt. symbols | XPE |
| Entrez | 1642 |
| HUGO | 2717 |
| OMIM | 600045 |
| RefSeq | NM_001923 |
| UniProt | Q16531 |
| Other data | |
| Locus | Chr. 11 q12-q13 |
| damage-specific DNA binding protein 2, 48kDa | |
|---|---|
| Identifiers | |
| Symbol | DDB2 |
| Alt. symbols | DBB, UV-DDB2, FLJ34321 |
| Entrez | 1643 |
| HUGO | 2718 |
| OMIM | 600811 |
| RefSeq | NM_000107 |
| UniProt | Q92466 |
| Other data | |
| Locus | Chr. 11 p12-p11 |
DNA damage-binding protein is a protein complex that is responsible for repair of UV-damaged DNA.[1] This complex is composed of two protein subunits, a large subunit DDB1 and a small subunit DDB2. This complex functions in nucleotide excision repair.
References
- ↑ Dualan R, Brody T, Keeney S, Nichols AF, Admon A, Linn S (Feb 1996). "Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein". Genomics 29 (1): 62–9. doi:10.1006/geno.1995.1215. PMID 8530102.
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