Cunninghamella
| Cunninghamella | |
|---|---|
 | |
| Cunninghamella echinulata | |
| Scientific classification | |
| Kingdom: | Fungi |
| Order: | Mucorales |
| Family: | Cunninghamellaceae |
| Genus: | Cunninghamella Matr. (1903) |
| Type species | |
| Cunninghamella africana Matr. 1903 | |
| Synonyms[1] | |
| |
Cunninghamella is a genus of fungi in the order Mucorales, and the family Cunninghamellaceae.[2] The genus was circumscribed by French mycologist Alphonse Louis Paul Matruchot in 1903.[3]
Species
As of 2015, Index Fungorum lists 13 valid species of Cunninghamella:[4]
- C. binarieae R.Y.Zheng 2001
- C. blakesleeana
- C. candida Yosh.Yamam. 1929
- C. clavata R.Y.Zheng & G.Q.Chen 1998
- C. echinulata (Thaxt.) Thaxt. ex Blakeslee 1905
- C. elegans Lendn. 1905
- C. homothallica Komin. & Tubaki 1952
- C. intermedia K.B.Deshp. & Mantri 1966
- C. multiverticillata R.Y.Zheng & G.Q. Chen 2001
- C. phaeospora Boedijn 1959
- C. polymorpha Pišpek 1929
- C. septata R.Y.Zheng 2001
- C. vesiculosa P.C.Misra 1966
Uses
Members of this genus are often used in studies investigating the metabolism of drugs, because these species metabolize a wide range of drugs in manners similar to mammalian enzyme systems.[5] Many species are also capable of oxidizing polycyclic aromatic hydrocarbons, a class of stable organic molecules that tends to persist in the environment and contains many known carcinogenic and mutagenic compounds.[6]
The presence of a cytochrome P-450 has been demonstrated in C. bainieri.[7]
References
- ↑ "Synonymy: Cunninghamella Matr.". Species Fungorum. CAB International. Retrieved 2015-09-21.
- ↑ Cunninghamella at the US National Library of Medicine Medical Subject Headings (MeSH)
- ↑ Matruchot L. (1903). "Une Mucorinée purement conidienne. Cunninghamella africana". Annales Mycologici (in French) 1: 45–60.
- ↑ "Species Fungorum (version 26th August 2015). In: Species 2000 & ITIS Catalogue of Life". Retrieved 2015-09-21.
- ↑ Asha S, Vidyavathi M (2009). "Cunninghamella--a microbial model for drug metabolism studies--a review". Biotechnol. Adv. 27 (1): 16–29. doi:10.1016/j.biotechadv.2008.07.005. PMID 18775773. Retrieved 2009-03-17.
- ↑ Cerniglia, Carl E. (1992). "Biodegradation of polycyclic aromatic hydrocarbons". Biodegradation 3 (2–3): 351–368. doi:10.1007/BF00129093.
- ↑ Aryl hydrocarbon hydroxylase activity in the fungus Cunninghamella bainieri: Evidence for the presence of cytochrome P-450. J.P. Ferris, L.H. MacDonald, M.A. Patrie and M.A. Martin, Archives of Biochemistry and Biophysics, Volume 175, Issue 2, August 1976, pages 443-452, doi:10.1016/0003-9861(76)90532-4
External links
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