Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone
Names | |
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IUPAC name
2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile | |
Identifiers | |
370-86-5 | |
ChEBI | CHEBI:75458 |
ChEMBL | ChEMBL457504 |
ChemSpider | 3213 |
Jmol interactive 3D | Image Image |
MeSH | FCCP |
PubChem | 3330 |
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Properties | |
C10H5F3N4O | |
Molar mass | 254.16811 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone (FCCP) is an ionophore that is a mobile ion carrier. It is referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through a cell membrane before they can be used to provide the energy for oxidative phosphorylation.[2] It is a nitrile and hydrazone. FCCP was first described in 1962 by Heytler.[3]
References
- ↑ FCCP - Compound Summary, PubChem.
- ↑ MeSH Descriptor Data, MeSH.
- ↑ Heytler, P G (1962). "A new class of uncoupling agents — Carbonyl cyanide phenylhydrazones". Biochemical and Biophysical Research Communications 7 (4): 272–275. doi:10.1016/0006-291X(62)90189-4.
See also
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