CNOT8

CCR4-NOT transcription complex, subunit 8
Identifiers
Symbols CNOT8 ; CAF1; CALIF; Caf1b; POP2; hCAF1
External IDs OMIM: 603731 MGI: 1916375 HomoloGene: 48304 GeneCards: CNOT8 Gene
EC number 3.1.13.4
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 9337 69125
Ensembl ENSG00000155508 ENSMUSG00000020515
UniProt Q9UFF9 Q9D8X5
RefSeq (mRNA) NM_001301073 NM_026949
RefSeq (protein) NP_001288002 NP_081225
Location (UCSC) Chr 5:
154.86 – 154.88 Mb
Chr 11:
58.1 – 58.12 Mb
PubMed search

CCR4-NOT transcription complex subunit 8 is a protein that in humans is encoded by the CNOT8 gene.[1][2][3]

Interactions

CNOT8 has been shown to interact with BTG2,[4] BTG1,[4][5] CNOT1[2][6] and CNOT3.[2]

References

  1. Fidler C, Wainscoat JS, Boultwood J (May 1999). "The human POP2 gene: identification, sequencing, and mapping to the critical region of the 5q- syndrome". Genomics 56 (1): 134–6. doi:10.1006/geno.1998.5687. PMID 10036195.
  2. 1 2 3 Albert TK, Lemaire M, van Berkum NL, Gentz R, Collart MA, Timmers HT (March 2000). "Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits". Nucleic Acids Res. 28 (3): 809–17. doi:10.1093/nar/28.3.809. PMC 102560. PMID 10637334.
  3. "Entrez Gene: CNOT8 CCR4-NOT transcription complex, subunit 8".
  4. 1 2 Prévôt D, Morel AP, Voeltzel T, Rostan MC, Rimokh R, Magaud JP, Corbo L (March 2001). "Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway". J. Biol. Chem. 276 (13): 9640–8. doi:10.1074/jbc.M008201200. PMID 11136725.
  5. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  6. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

Further reading


This article is issued from Wikipedia - version of the Monday, October 26, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.