CDH9
| Cadherin 9, type 2 (T1-cadherin) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | CDH9 ; MGC125386 | ||||||||||||
| External IDs | OMIM: 609974 MGI: 107433 HomoloGene: 9450 GeneCards: CDH9 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 1007 | 12565 | |||||||||||
| Ensembl | ENSG00000113100 | ENSMUSG00000025370 | |||||||||||
| UniProt | Q9ULB4 | P70407 | |||||||||||
| RefSeq (mRNA) | NM_016279 | NM_009869 | |||||||||||
| RefSeq (protein) | NP_057363 | NP_033999 | |||||||||||
| Location (UCSC) |
Chr 5: 26.88 – 27.12 Mb |
Chr 15: 16.78 – 16.86 Mb | |||||||||||
| PubMed search | |||||||||||||
Cadherin 9 is a protein that in humans is encoded by the CDH9 gene.[1][2]
Clinical significance
An association with autism has been suggested.[3]
See also
References
- ↑ "Entrez Gene: cadherin 9".
- ↑ Suzuki S, Sano K, Tanihara H (April 1991). "Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue". Cell Regul. 2 (4): 261–70. doi:10.1091/mbc.2.4.261. PMC 361775. PMID 2059658.
- ↑ Wang K, Zhang H, Ma D; et al. (May 2009). "Common genetic variants on 5p14.1 associate with autism spectrum disorders". Nature 459 (7246): 528–33. doi:10.1038/nature07999. PMC 2943511. PMID 19404256.
Further reading
- Nollet F, Kools P, van Roy F (2000). "Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.". J. Mol. Biol. 299 (3): 551–72. doi:10.1006/jmbi.2000.3777. PMID 10835267.
- Shimoyama Y, Tsujimoto G, Kitajima M, Natori M (2000). "Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins.". Biochem. J. 349 (Pt 1): 159–67. doi:10.1042/0264-6021:3490159. PMC 1221133. PMID 10861224.
- Wang K, Zhang H, Ma D; et al. (2009). "Common genetic variants on 5p14.1 associate with autism spectrum disorders.". Nature 459 (7246): 528–33. doi:10.1038/nature07999. PMC 2943511. PMID 19404256.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Wang K, Zhang H, Bloss CS; et al. (2010). "A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.". Mol. Psychiatry 16 (9): HASH(0x2b2fb6928aa0). doi:10.1038/mp.2010.107. PMID 21079607.
- Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ali J, Liao F, Martens E, Muller WA (1997). "Vascular endothelial cadherin (VE-cadherin): cloning and role in endothelial cell-cell adhesion.". Microcirculation 4 (2): 267–77. doi:10.3109/10739689709146790. PMID 9219219.
- Thedieck C, Kalbacher H, Kuczyk M; et al. (2007). Zoccali, Carmine, ed. "Cadherin-9 is a novel cell surface marker for the heterogeneous pool of renal fibroblasts.". PLoS ONE 2 (7): e657. doi:10.1371/journal.pone.0000657. PMC 1924602. PMID 17668045.
- Hülsken J, Birchmeier W, Behrens J (1994). "E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton". J. Cell Biol. 127 (6 Pt 2): 2061–9. doi:10.1083/jcb.127.6.2061. PMC 2120290. PMID 7806582.
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