CDCA3

Cell division cycle associated 3

Identifiers

CDCA3 ; GRCC8; TOME-1

External IDs

OMIM: 607749 MGI: 1315198 HomoloGene: 8403 GeneCards: CDCA3 Gene

Gene ontology
Molecular function	• molecular_function • protein binding
Cellular component	• cellular_component • cytosol
Biological process	• mitotic nuclear division • biological_process • protein ubiquitination • cell division
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000111665

ENSMUSG00000023505

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 12:
6.84 – 6.85 Mb

Chr 6:
124.83 – 124.83 Mb

PubMed search

Cell division cycle-associated protein 3 is a protein that in humans is encoded by the CDCA3 gene.^[1]^[2]^[3]

Interactions

CDCA3 has been shown to interact with SKP1A.^[4]

References

↑ Ansari-Lari MA, Shen Y, Muzny DM, Lee W, Gibbs RA (May 1997). "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination". Genome Res 7 (3): 268–80. doi:10.1101/gr.7.3.268. PMID 9074930.
↑ Walker MG (Aug 2002). "Drug target discovery by gene expression analysis: cell cycle genes". Curr Cancer Drug Targets 1 (1): 73–83. doi:10.2174/1568009013334241. PMID 12188893.
↑ "Entrez Gene: CDCA3 cell division cycle associated 3".
↑ Ayad, Nagi G; Rankin Susannah; Murakami Monica; Jebanathirajah Judith; Gygi Steven; Kirschner Marc W (Apr 2003). "Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC". Cell (United States) 113 (1): 101–13. doi:10.1016/S0092-8674(03)00232-0. ISSN 0092-8674. PMID 12679038.

Further reading

Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Yoshida K (2005). "Cell-cycle-dependent regulation of the human and mouse Tome-1 promoters.". FEBS Lett. 579 (6): 1488–92. doi:10.1016/j.febslet.2005.01.055. PMID 15733861.
Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Ayad NG, Rankin S, Murakami M; et al. (2003). "Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC.". Cell 113 (1): 101–13. doi:10.1016/S0092-8674(03)00232-0. PMID 12679038.
Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ansari-Lari MA, Muzny DM, Lu J; et al. (1996). "A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13.". Genome Res. 6 (4): 314–26. doi:10.1101/gr.6.4.314. PMID 8723724.

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