Bropirimine

Bropirimine
Systematic (IUPAC) name

2-amino-5-bromo-6-phenylpyrimidin-4(1H)-one
Identifiers
CAS Number	56741-95-8
ATC code	None
ChemSpider	58914
UNII	J57CTF25XJ^Y
ChEMBL	CHEMBL37387
Chemical data
Formula	C₁₀H₈BrN₃O
Molar mass	266.09 g/mol
SMILES Br\C2=C(/c1ccccc1)N\C(=N/C2=O)N
InChI InChI=1S/C10H8BrN3O/c11-7-8(6-4-2-1-3-5-6)13-10(12)14-9(7)15/h1-5H,(H3,12,13,14,15) Key:CIUUIPMOFZIWIZ-UHFFFAOYSA-N

Bropirimine is an experimental drug with anti-cancer and antiviral properties.^[1] It is an orally effective immunomodulator and is being tried in bladder cancers.^[2]

Chemistry

Skulnick, Harvey I.; Weed, Sheldon D.; Eidson, Emerson E.; Renis, Harold E.; Stringfellow, Dale A.; Wierenga, Wendell (1985). "Pyrimidinones. 1. 2-Amino-5-halo-6-aryl-4(3H)-pyrimidinones. Interferon-inducing antiviral agents". Journal of Medicinal Chemistry 28 (12): 1864–9. doi:10.1021/jm00150a018. PMID 2999405.

References

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