Betamethadol

Betamethadol
Systematic (IUPAC) name
(3S,6R)-6-(dimethylamino)-4,4-diphenyl-3-heptanol
Clinical data
Legal status
Identifiers
CAS Number 17199-55-2
ATC code None
PubChem CID 10064061
ChemSpider 8239601
ChEMBL CHEMBL162243
Chemical data
Formula C21H29NO
Molar mass 311.461 g/mol

Betamethadol (INN), or β-methadol, also known as betametadol, is a synthetic opioid analgesic.[1] It is an isomer of dimepheptanol (methadol), the other being alphamethadol (α-methadol).[2] Betamethadol is composed of two isomers itself, L-β-methadol, and D-β-methadol.[2] Based on structure-activity relationships it can be inferred that both isomers are likely to be active as opioid analgesics, similarly to those of betacetylmethadol (β-acetylmethadol).[3]

See also

References

  1. F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1294. ISBN 978-0-412-46630-4. Retrieved 15 May 2012.
  2. 1 2 United Nations Office on Drugs and Crime (2006). Dictionnaire Multilingue Des Stupéfiants Et Des Substances Psychotropes Placés Sous Contrôle International. United Nations Publications. p. 103. ISBN 978-92-1-048117-5. Retrieved 15 May 2012.
  3. Newman JL, Vann RE, May EL, Beardsley PM (October 2002). "Heroin discriminative stimulus effects of methadone, LAAM and other isomers of acetylmethadol in rats". Psychopharmacology 164 (1): 108–14. doi:10.1007/s00213-002-1198-8. PMID 12373424.



This article is issued from Wikipedia - version of the Monday, October 12, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.