Aprobarbital
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| Systematic (IUPAC) name | |
|---|---|
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5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione | |
| Clinical data | |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Identifiers | |
| CAS Number |
77-02-1  |
| ATC code | N05CA05 |
| PubChem | CID 6464 |
| DrugBank |
DB01352 |
| ChemSpider |
6221 |
| UNII |
Q0YKG9L6RF |
| KEGG |
D00698 |
| ChEBI |
CHEBI:2791 |
| ChEMBL |
CHEMBL7863 |
| Synonyms | aprobarbital, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid |
| Chemical data | |
| Formula | C10H14N2O3 |
| Molar mass | 210.23 g/mol |
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Aprobarbital (as known in the United States, or aprobarbitone (as known elsewhere), sold as Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia.[1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.
References
- ↑ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.
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