alpha-Pyrrolidinopentiothiophenone
 | |
| Systematic (IUPAC) name | |
|---|---|
|
2-(pyrrolidin-1-yl)-1-(thiophen-2-yl)pentan-1-one | |
| Clinical data | |
| Legal status |
|
| Identifiers | |
| CAS Number | 1400742-66-6 |
| ChemSpider | 29738196 |
| Chemical data | |
| Formula | C13H19NOS |
| Molar mass | 237.4 g/mol |
| |
| |
α-Pyrrolidinopentiothiophenone (also known as α-PVT) is a synthetic stimulant of the cathinone class that has been sold online as a designer drug.[1][2][3] It is a analogue of α-PVP where the phenyl ring has been replaced by thiophene.
α-PVT was first identified in Japan in 2013.[4] Its metabolism has been described in literature.[5][6]
Legality
Sweden's public health agency suggested classifying α-PVT as hazardous substance on November 10, 2014.[7]
As of October 2015 α-PVT is a controlled substance in China.[8]
α-PVT is illegal in Switzerland as of December 2015.[9]
See also
- α-Pyrrolidinopropiophenone (α-PPP)
- α-Pyrrolidinobutiophenone (α-PBP)
- α-Pyrrolidinohexiophenone (α-PHP)
- Methiopropamine
- Naphyrone (O-2482)
- Pyrovalerone (O-2371)
- Thiopropamine
- Thiothinone
References
- ↑ "α-Pyrrolidinopentiothiophenone". Cayman Chemical. Retrieved 29 June 2015.
- ↑ Marta Concheiro, Marisol Castaneto, Robert Kronstrand, Marilyn A. Huestis (June 2015). "Simultaneous determination of 40 novel psychoactive stimulants in urine by liquid chromatography-high resolution mass spectrometry and library matching.". Journal of Chromatography A 1397 (5): 32–42. doi:10.1016/j.chroma.2015.04.002. PMID 25931378.
- ↑ Takahiro Doi, Akiko Asada, Akihiro Takeda, Takaomi Tagami, Munehiro Katagi, Shuntaro Matsuta, Hiroe Kamata, Masami Kawaguchi, Yuka Satsuki, Yoshiyuki Sawabe, Hirotaka Obana (January 2016). "Identification and characterization of α-PVT, α-PBT, and their bromothienyl analogs found in illicit drug products". Forensic Toxicology 34 (1): 76–93. doi:10.1007/s11419-015-0288-3.
- ↑ Nahoko Uchiyama, Satoru Matsuda, Maiko Kawamura, Ruri Kikura-Hanajiri, Yukihiro Goda (July 2013). "Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products". Forensic Toxicology 31 (2): 223–240. doi:10.1007/s11419-013-0182-9.
- ↑ Takahiro Takayama, Mayu Suzuki, Kenichiro Todoroki, Koichi Inoue, Jun Zhe Min, Ruri Kikura-Hanajiri, Yukihiro Goda, Toshimasa Toyo'oka (June 2014). "UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome.". Biomedical Chromatography 28 (6): 831–838. doi:10.1002/bmc.3155. PMID 24861751.
- ↑ Madeleine J Swortwood, Jeremy Carlier, Kayla N Ellefsen, Ariane Wohlfarth, Xingxing Diao, Marta Concheiro-Guisan, Robert Kronstrand, Marilyn A Huestis (December 2015). "In vitro, in vivo and in silico metabolic profiling of α-pyrrolidinopentiothiophenone, a novel thiophene stimulant". Bioanalysis. doi:10.4155/bio.15.237. PMID 26648097.
- ↑ "Cannabinoider föreslås bli klassade som hälsofarlig vara" (in Swedish). Retrieved 29 June 2015.
- ↑ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015.
- ↑ "Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien" (in German). Der Bundesrat.
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